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1. Personal history
Timothy L. Vollmer, M.D. CURRICULUM VITAE
University of Colorado School of Medicine 12631 East 17th Avenue, Mail Stop B185 Aurora, Colorado 80045


2. Education
 University of Wyoming, Laramie, WY (B.A. Zoology with Highest Honors), 1973-1977
 Stanford University School of Medicine, Stanford, CA (M.D.), 1977-1982
 Intern in Internal Medicine, Yale New Haven Hospital, New Haven CT, 1982-1983
 Resident in Neurology, Stanford University Hospital, Stanford, CA, 1983-1985
 Post Doctoral Fellow in Neuroimmunology, University Hospital, Stanford, CA, 1985-1986
 Chief Resident in Neurology, Stanford University Hospital, Stanford, CA, 1986-1987
 ACPE Physician Executive Course I, 1995
 Yale School of Medicine and Yale School of Business Physician Executive Course, 1997
3. Academic Appointments
 Assistant Professor, Department of Neurology, Yale University School of Medicine, New Haven, CT, 1987—1993
 Medical Director, Rocky Mountain Multiple Sclerosis Center, Swedish Medical Center, Englewood, CO, 1993—1995
 Associate Clinical Professor, Department of Neurology, University of Colorado, Denver, CO, 1993—1995
 Associate Professor, Department of Neurology, Yale University School of Medicine, New Haven, CT, 1996—2002
 Vice Chairman-Clinical Affairs, Department of Neurology, Yale University , New Haven, CT, 1996—2002
 Director, Yale Multiple Sclerosis Research Center, New Haven, CT, 1996—2002
 Associate Director for Clinical Studies, Center of Excellence on Restoration of Function in
Spinal Cord Injury and Multiple Sclerosis, U.S. Dept. of Veterans Affairs, Division of Rehabilitation Research and Development, Connecticut VA Healthcare System, West Haven, CT, 1996—2002
 Chair, Division of Neurology, Barrow Neurological Institute at St. Joseph’s Hospital and Medical Center, Phoenix, AZ August, 2002—March, 2007
 Associate Residency Program Director, Barrow Neurological Institute at St. Joseph Hospital and Medical Center, Phoenix, AS, January, 2004—August, 2008
 Director, Neuroimmunology Program, Barrow Neurological Institute at St. Joseph Hospital and Medical Center, Phoenix, AZ, August, 2002—August, 2008
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 Van Denburgh Professor of Neurology, Barrow Neurological Institute at St. Joseph Hospital and Medical Center, Phoenix, AZ, March 2002—August, 2008
 Co-Director, Rocky Mountain MS Center at Anschutz Medical Campus 2008—Present
 Medical Director, Rocky Mountain MS Center 2008—Present
 Professor of Neurology, University of Colorado Denver 2008—Present
 Director, Neurosciences Clinical Research, University of Colorado Denver 2010—Present
Other Professional Positions
 Nancy Davis Center Without Walls Investigator, 1994—2002
 Director, NARCOMS Project for Consortium of MS Centers 1996—2011
Honors, Recognitions and Awards
 Voted in top quartile of attending physicians by medical students at University of Colorado School of medicine for academic year 2010-2011
 Accelerated Cure Project for Multiple Sclerosis PHYSICIAN OF DISTINCTION AWARD, 2011
 Best Doctors, Top 1% of neurologists ranked nationally by US News & World Report and Castle Connolly Medical, Ltd. 2011
 Fellow, American Academy of Neurology 2009
 University of Colorado Department of Neurology Teaching Award 2009
 Diplomat, American Academy of Neurology, Section of Multiple Sclerosis 2001
 Best Doctors in American 2003—2004
 National Multiple Sclerosis Society Volunteer Hall of Fame
 Who’s Who in North America
 Who’s Who in Science
 Who’s Who in Medicine
 Best Doctors in New York, Castle Connolly Medical LTD
 2000 Outstanding Scientists of the 21st Century-First Edition (Melrose Press, LTD., Ely, Cams.
UK)
 American Neurology Association Fellow
 Scholars Program (Appointment (Stanford University)
 Dean’s Fellowship (Stanford University)
 Alpha Epsilon Delta
 Omicron Delta Kappa
 Phi Beta Kappa
 Phi Kappa Phi
 University of Wyoming Honors Scholarship
Memberships in Professional Organizations
 Colorado Society of Clinical Neurologists
 Arizona Medical Association 2003-2004
 American Academy of Neurology
 American Association of Immunology
 American Neurological Association
 American Society of Experimental NeuroTherapeutics
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 Consortium of Multiple Sclerosis Centers
 International Society for Neuro Immunology
 Society for Neuroscience
 Royal Academy of Physicians
7. Major committee and service responsibilities
 University of Colorado School of Medicine Admissions Committee, 2010--
 Advisory Committee, 109MS201, Biogen Idec
 NARCOMS Team member
 NARCOMS Steering Committee (?—2010)
 Consortium of Multiple Sclerosis Centers (CMSC Board of Governors – member
 Clinical Advisory Committee—National Multiple Sclerosis Society, Local Chapter
 Clinical Advisory Committee—National Multiple Sclerosis Society, Member
 Steering Committee, FTY720 Studies, Novartis
 National Professional Advisory Committee-National MS Society
 Yale Medical Student Preclinical Curriculum Committee Chairman, 1992-1993
 Yale School of Medicine Senior Clinician Committee, Member, 1993/01996-2002
 Yale Clinical Research Policies Review Committee 2000
 Councilor, MS Section, American Academy of Neurology, 2001
 Data Safety and Monitoring Committee, ARA V A, Adventis, Chairman, 2001-2002
 Yale Dept of Neurology Clilnical Management Team, Chairman, 1996-2002
 Yale Medical Student Admission Committee, Member, 1998-2002
 Yale Faculty Practice Plan Contracting Committee, Member, 1999-2002
 Yale Provost’s Standing Committee on Conflict of Interest, Member, 2000-2002
 Yale School of Medicine Credentialing committee, Member, 1999-2002
 Clinical Review Committee, CHAPS and CHAMPIONS Study, 1998-2002
 Yale School of Medicine Strategic Planning Committee, Member, 1996
8. Licensure and board certification
 State of Colorado licensure
 Board certified, American Board of Psychiatry and Neurology, 1991
9. Review and referee work
 Editor, Multiple Sclerosis Quarterly Report (MSQR); 1999—2005
 Co-Editor, Multiple Sclerosis Quarterly Report (MSQR); January, 2005—Present
 Editorial Board, European Journal of Neurology; 2010--present
10. Invited extramural lectures, presentations and visiting professorships
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“New Treatment Strategies in MS” presentation at New Perspectives in Multiple Sclerosis: Epidemiology, Pathology, Imaging and Treatment Strategies CME symposia, sponsored by State University of New York, University at Buffalo. New Orleans, LA., Sept. 11, 2010 Johns Hopkins University CME videotaped presentation sponsored by MedicalLogix: “Advances in MS: Emerging Strategies for Neuroprotection and Neuroregeneration” Grand Rounds presentation to University of California San Diego School of Medicine August, 12, 2011
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10.1. Conferences organized and/or chaired
1. Yale Clinical Neuroimmunology Conference, Yale School of Medicine, Chair, 1993
2. International Committee on Databases in MS, Inaugural Meeting, Venice, Italy, Chair, 1999
3. International Committee on Databases in MS, Second Annual Meeting, Fort Worth, Texas, Chair, 2001
4. Yale Neuroimmunology Conference, Yale School of Medicine, Chair, 2001
5. Yale International Conference on Schwann Cell Transplantation in MS, Yale School of Medicine,
2001
6. 29th Annual Barrow Neurological Institute Neurology Symposium, Barrow Neurological Institute,
Committee Member, 2003
7. 30th Annual Barrow Neurological Institute Neurology Symposium, Barrow Neurological Institute,
Committee Member, 2004
8. 31st Annual Barrow Neurological Institute Neurology Symposium, Barrow Neurological Institute,
Committee Member, 2005
9. 32nd Annual Barrow Neurological Institute Neurology Symposium, Barrow Neurological Institute,
Committee Member, 2006
10. 33rd Annual Barrow Neurological Institute Neurology Symposium, Barrow Neurological Institute,
Committee Member, 2007
11. Exercise as a Prescriptive Therapy in MS: What We Know and What We Need to Know. A Consensus
Conference, organizer and presenter. Denver, Colorado October 2-3, 2010
11. Teaching record
 Grand Rounds presentation-University of Colorado Department of Neurology
 December 11, 2009
 December 12, 2010: “Immunotherapies of MS: New Opportunities and New Risks”
 December 7, 2011: “Is Multiple Sclerosis a Disease of Oligodendrocytes, Neurons or
Astrocytes? Why Does it Matter?”
 Invited Grand Rounds presentations
 August 12, 2011, University of California San Diego
 Resident Education presentations
 June 3, 2009. Goals of Immunotherapy in MS Using FDA Approved DMANS;
 June, 2010 Our Evolving Understanding of MS, Implications for Future Therapies;  October 6, 2010. Case presentations
 December 8, 2010: Immunological therapy in MS
 Student Teaching
 October 7, 2009 4th year student lecture, Path 8001, CNS Analysis, University of Colorado School of Medicine
 October 11, 2011 4th year student lecture, University of Colorado School of Medicine Clinical Laboratory Medicine, Pathology 8001, CSF Analysis.
 January 31, 2012 Neuroscience Graduate Education Lecture, University of Colorado School of Medicine
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 Attending Neurologist at University Hospital
 March 1—March 15, 2009  June 1—June 15, 2009
 Oct 4—Oct 7, 2010
 Oct 18, 2010
 Oct. 19—Oct. 31, 2010
 January 1—January 15, 2011
 Neuro Service/Stroke Call August 18, 2011, September 14, 2011, October 31, 2011,
December 21, 2011
 Mentees/trainees
 Jonathan Goldstein, M.D., Associate Professor of Neurology, Yale School of Medicine
 Jana Preiningerova, M.D. formerly Assistant Professor of Neurology, Yale School of
Medicine. Currently residing in Eastern Europe
 Robert Bomprezzi, M.D., PhD. Assistant Professor of Neurology, Barrow
Neurological Institute
 Wenhua Piao, PhD
 Wei Liu, PhD. Faculty, Albert Einstein College of Medicine
 Mrinalini Kala, PhD. Faculty, University of California San Francisco
 Youn Jee, M.D., PhD. Assistant Professor, Cheju National University, School of
Medicine, Korea
 3rd year medical students at University of Colorado 2010--2011:
Daren Eblovi, Brent Fowler, Julian Maendel, Yihan Lin, Samuel Mast, Matthew Percy,
Amy Reppert, Benjamin Snyder, Tobin Strom, Tyra Thorstad, Asa Ware.
 Residents, University of Colorado School of Medicine, 2010-2011:
Charles Braun, Haley Burke, Emily Gertsch, Takamasa Higashimori, Kimberly Horiuchi, Drew Kern, Angel Pulido, Peter Bergman, Emily Lampe, Eryn Lonnquist, Danielle McDermott, Marius Birlea, Adam Graham, Aaron Haug, Wesley Reynolds, Katie Polovitz, Teri Schreiner, 2010--2011
 David Case, Mentee Resident University of Colorado School of Medicine 2008—2009; 2009—2010; 2010—2011
 Preceptor for Kiara Foltyn 1st year medical student, University of Colorado School of Medicine, 2010
 Matthew West, M.D., Neuro-Immunology Fellow, 2010--2011
 Teri Schreiner, M.D., Neuro-Immunology Fellow, 2011—2012
 Preceptor for Jacob Pellinen, 2nd year medical student, University of Colorado School
of Medicine 2011-2012
 Preceptor for Jeremy Hua 1st year medical student, University of Colorado School of
Medicine, 2011--
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12. Grant support—Current as Primary Investigator
MS-LAQ-302E, TEVA Neuroscience (extension) Vollmer (PI) 12/01/2009-11/30/2012
This project is an extension of the MS-LAQ-302 (BRAVO) study to evaluate the long-term safety, tolerability and effect on disease course of daily oral laquinimod 0.6 mg in subjects with relapsing multiple sclerosis
101-MS-402 TYGRIS: TYSABRI, Biogen Idec, Inc. Vollmer (PI) 11/13/2008-11/12/2011
This project assesses the incidence and pattern of serious infections, malignancies, and other serious adverse events (SAEs) in patients with MS treated with TYSABRI® (natalizumab).
CAMMS32409, Genzyme Vollmer (PI 02/07/2011- 02/06/2014 This project is an extension protocol for Multiple Sclerosis patients who participated in Genzyme- Sponsored studies of Alemtuzumab, such as CAMMS32400507
ONO-4641 POU006, Ono Pharmaceutical Co Vollmer (PI) 01/2010-04/30/2013 This project is a flexible-dose titration study of the safety and tolerability of ONO-4641 in patients with a relapsing form of multiple sclerosis
ONO-4641POU007 (Extension) Ono Pharmaceutical Vollmer (PI) 03/01/2011-2/28/2014 To evaluate continuing safety and efficacy of ONO-4641 in patients who have completed an initial 26- week study (ONO-4641POU006)
101JC401, Biogen Idec Vollmer (PI) 05/01/2010-04/30/2013 JVC Antibody Program in Patients with Relapsing Multiple Sclerosis Receiving or Considering Treatment with Tysabri®: STRATIFY-1
101JC402, Biogen Idec Vollmer (PI) 07/01/2010-06/30/2013 JCV Antibody Program in Patients with Relapsing Multiple Sclerosis Receiving or Considering Treatment with Tysabri®: STRATIFY-2
109MS201 Biogen Idec Vollmer (PI) 06/01/2010-05/31-2015 To evaluate the safety and tolerability of BG00012 administered in combination with IFNβ or GA in subjects with remitting-relapsing multiple sclerosis. EXPLORE
Rocky Mountain Network for Neuroscience Clinical Studies (RMNNCS).
NIH/NINDS 1U10NS077277-01 Vollmer (PI) 9/30/11-9/30/18
10-1143, Gateway II Teva Vollmer (PI) 10/1/2011-3-31-2014 Randomized study comparing rituximab induction therapy followed by glatiramer acetate to glairamer acetate monotherapy in RRMS
12.1Grant support—Past
Duloxetine in patients with central neuropathic pain Vollmer (PI) 10/31/2008-10/30/2011
Lilly Research Laboratories
This project assesses the efficacy of duloxetine 60 mg once daily (QD) compared with placebo on the reduction of pain severity as measured by the weekly mean of the daily 24-hour average pain scores in patients with central neuropathic pain in MS.
A 12-month double-blind, randomized, multicenter, active-controlled, parallel-group study comparing the efficacy and safety of 0.5 mg and 1.25 mg fingolimod (FTY720) administered orally once daily versus interferon β-1a (Avonex®) administered IM once weekly in patients with relapsing-remitting multiple sclerosis with optional Extension Phase, Novartis , (Sub Investigator)
A Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Progressive Multiple Sclerosis, BioMS Technology Corp., (Sub Investigator)
Improved Diagnosis of Multiple Sclerosis Using Magnetoencephalography (MEG) and the Synchronous Neural Interaction TM Test: MS Template Development Study. Orasi (Sub Investigator)
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5 A 14 week Randomized, Double-Blind, Placebo-Controlled Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Nerispiridine 50 mgm, 100 mg. and 200 mg in Patients With Multiple Sclerosis, Sanofi Aventis (Principal Investigator)
6 A Phase 1 Open-Label, Flexible-Dose Titration Study of the Safety and Tolerability of ONO-4641 in Patients with a Relapsing Form of Multiple Sclerosis, Ono Pharma USA. ONO 4641 (Principal Investigator)
7 A Study with IPX056 in Subjects with Spasticity Associated with Multiple Sclerosis (Principal Investigator)
8 A Phase II, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Safety, Tolerability and Efficacy Study on Add-on Cladribine Tablet Therapy with Rebif® New Formulation in Multiple Sclerosis Subjects with Active Disease, Serono International S.A., Serono, Inc., (Principal Investigator)
9. A Phase 2 Randomized, Double-Blinded, Placebo-Controlled, Multi-Center Study of Subcutaneous Daclizumab® in Patients with Active, Relapsing Forms of Multiple Sclerosis, PDL BioPharma, Inc., (Principal Investigator)
10. Biomarkers in Multiple Sclerosis, Division of Intramural Research (DIR), NIH/NINDS, (Principal Investigator)
11. Online Validation of Multiple Sclerosis International Quality of Life (MuSI-QoL) Questionnaire, Serono/Pfizer, (Principal Investigator)
12. A Prospective Study of Quality of Life and Cost of Disease in a Selected Group of MS Patients Treated with Novantrone, Serono International S.A., Serono, Inc. (Principal Investigator)
13. Development of Peripheral Blood Diagnostics and Biomarkers for Alzheimer's Disease, Arizona Biomedical Research Commission (ABRC), (Subinvestigator)
14. Double-Blind, Placebo-Controlled, 20-Week, Parallel Group Study to Evaluate Safety, Tolerability and Activity of Oral Fampridine-SR in Subjects with Multiple Sclerosis, Acorda Therapeutics, Inc. (Principal Investigator)
15. Open-Label Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Subjects with Multiple-Sclerosis, Acorda Therapeutics, Inc. (Principal Investigator)
16. A Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of AVP-923 (Dextromethorphan/Quinidine) in the Treatment of Pseudobulbar Affect in Patients with Multiple Sclerosis (Principal Investigator)
17. A Phase II/III, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Rituximab (MabThera®/Rituxan®) in Adults with Primary Progressive Multiple Sclerosis, Genentech, Inc., (Principal Investigator)
18. A Phase II, Proof-of-Concept, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Rituximab (MabThera®/Rituxan®) in Adults with Relapsing-Remitting Multiple Sclerosis, Genentech, Inc., (Principal Investigator)
19. A Cross Sectional Study to Evaluate the Persistence of Immunological Effects of Glatiramer Acetate (Copaxone®) in Patients with Relapsing Forms of Multiple Sclerosis , Barrow Neurological Foundation, (Principal Investigator)
20. Specimen and Data Collection and Archiving for Immunological Investigations Aiming to Understand the Immunological Mechanism of Multiple Sclerosis (MS) and Identify New Targets For Immune Therapies for Multiple Sclerosis and Other Autoimmune Diseases and Neuroinflammatory Disorders, Barrow Neurological Foundation (Principal Investigator)
21. Gene Expression Assay of Patients with Multiple Sclerosis and Other Neurological Diseases, On and Off Immunological Therapy, Compared to Healthy Controls, Barrow Neurological Foundation/TGen, (Principal Investigator)
22. A Genomics Study of Blood Markers of Disease Activity in Multiple Sclerosis (Co-Principal Investigator)
23. Phase I Trial of Immunotherapy with BHT-3009 Alone or Combined with Atorvastatin in Patients with Multiple Sclerosis (Lead Investigator)
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24. International, randomized, multicenter, Phase IIIb study in patients with relapsing-remitting multiple- sclerosis comparing over a treatment period of 104 weeks: 1) Double-blinded safety, tolerability, and efficacy of Betaseron/Betaferon 250 ug (8MIU) and Betaseron/Betaferon 500 ug (16 MIU), both give subcutaneously every other day, and 2) Rater-blinded safety, tolerability, and efficacy of Betaseron/Betaferon s.c. every other day with Copaxone 20 mg s.c. once daily. (Principal Investigator)
25. A Randomized, Rater-blinded, Multicenter, Parallel-group Study Comparing the Efficacy and Safety of Betaseron® 250mg Subcutaneously Every Other Day with Avonex® 30mg Intramuscularly Once per Week in Relapsing-remitting Multiple Sclerosis Patients Previously Treated with Avonex®. (Principal Investigator)
26. A Phase II, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Preliminary Efficacy, Pharmacokinetics and Immunogenicity of BMS-188667 Administered to Subjects with Relapsing- Remitting Multiple Sclerosis" (Principal Investigator)
27. A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of NBI-5788- in Patients with Relapsing Multiple Sclerosis (Principal Investigator)
27. Multiple Sclerosis Instrument Quality of Life Project (MuSI-QoL) (Principal Investigator)
28. Phase IV, Multicenter, Open Label, Randomized Study Of Rebif 44 Mcg Administered Three Times
Per Week By Subcutaneous Injection Compared With Copaxone 20 Mg Administered Daily By Subcutaneous Injection In The Treatment Of Relapsing Remitting Multiple Sclerosis (Principal Investigator)
29. A Multi-Centered, Randomized, Two-Arm, Open Label Study to Evaluate the Safety, Tolerability and Efficacy of Induction Treatment with Mitoxantrone (Novantrone®) Preceding Treatment with Glatiramer Acetate (Copaxone®) versus Chronic Treatment with Glatiramer Acetate Alone in Relapsing Forms of Multiple Sclerosis Teva Neuroscience,( Lead Investigator)
30. Immunological Studies for a Multi-Centered, Randomized, Two-Arm, Open Label Study to Evaluate the Safety, Tolerability and Efficacy of Induction Treatment with Mitoxantrone (Novantrone) Preceding Treatment with Glatiramer Acetate (Copaxone) versus Chronic Treatment with Glatiramer Acetate Alone in Relapsing Forms of Multiple Sclerosis Teva Neuroscience,(Co-Principal Investigator)
31. Impact of Neutralizing Antibodies on Interferon Responsive Genes Highlights Biomarker Response, Biogen Idec, (Principal Investigator)
32. A Randomized, Double-Blind, Placebo-Controlled, Multi-center Study to Evaluate the Efficacy and Safety of Atorvastatin in Patients with Clinically Isolated Syndrome and High Risk of Conversion to Multiple Sclerosis, NIAID/ITN, (Principal Investigator)
33. A Multi-Center, Two Arm, Open Label Extension Study (to protocol NC_100) to Evaluate the Long- Term Safety and Efficacy of Short-Term Induction Treatment with Mitoxantrone (Novantrone®) Preceding Treatment With Glatiramer Acetate (Compaxone®) vs. Chronic Treatment with Glatiramer Acetate Alone in Relapsing Forms of Multiple Sclerosis, Teva Neuroscience (Lead Investigator)
34. A Phase I, Double-blind, Placebo-controlled Study Evaluating the Safety and Pharmacology of Single Dose Subcutaneously Administration of a Human Monoclonal Antibody to IL-12 (CNTO 1275) in Patients with Relapsing Forms of Multiple Sclerosis (Principal Investigator)
35. A 24-Week, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Dose Finding, Safety, Tolerability, and Efficacy Study of the Human Anti-IL-12 Antibody ABT-874 in Subjects With Multiple Sclerosis With a 24-Week Double-Blind, Active Extension Phase
36. Double-Blind, Placebo-Controlled, 20-Week, Parallel Group Study to Evaluate Safety, Tolerability and Activity of Oral Fampridine-SR in Subjects with Multiple Sclerosis
37. Double-Blind, Placebo-Controlled, 21-Week, Parallel Group Study to Evaluate Safety and Efficacy of Oral Fampridine-SR (10 mg B.I.D.) in Subjects with Multiple Sclerosis
38. A Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of AVP-923 (Dextromethorphan/Quinidine) in the Treatment of Pseudobulbar Affect in Patients with Multiple Sclerosis
39. A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of NBI-5788 in Patients with Relapsing Multiple Sclerosis
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40. A Randomised, Double-blind, Placebo-controlled, Parallel group, Dose-ranging Study to Investigate the MRI Efficacy and the Safety of Three Months Administration of SB-683699 (150-1200mg twice daily) in Subjects with Relapsing Multiple Sclerosis
41. An open-label study of leukocyte counts in the cerebrospinal fluid and blood of subjects with relapsing- remitting multiple sclerosis following treatment with firategrast
42. A Multi-Center, Randomized, Blinded, Parallel-Group Study of AVONEX® Compared with AVONEX® in Combination with Oral Methotrexate, Intravenous Methylprednisolone, or Both in Subjects with Relapsing-Remitting Multiple Sclerosis Who Have Breakthrough Disease on AVONEX® Monotherapy
43. Phase I Trial of Immunotherapy with BHT-3009 Alone or Combined with Atorvastatin in Patients with Multiple Sclerosis
44. An Open-Label, Multicenter Study to Assess the Safety of AVP-923 Dextromethorphan/Quinidine) in the Treatment of Pseudobulbar Affect (Principal Investigator)
45. An open-label and drug interaction study of natalizumab in combination with interferon-beta (Avonex®) in patients with multiple sclerosis.
46. A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Determine the Safety and Efficacy of Natalizumab in Subjects with Relapsing-Remitting Multiple Sclerosis (Principal Investigator)
47. A Phase II, Randomized, Double-Blind, Placebo Controlled Study To Evaluate The Preliminary Efficacy, Pharmacokinetics and Immunogenicity Of BMS-188667 Administered To Subjects With Relapsing-Remitting Multiple Sclerosis (Principal Investigator)
48. A 10 Year Open-Label Extension Study To Evaluate The Safety Of Copaxone And To Monitor The Neurologic Course of Disease In Multiple Sclerosis Patients Treated With Copaxone (Principal Investigator)
49. A Two-Arm, Cross-Over Design, Two Dose, Dose Escalation, Safety and Tolerability Study of Oral Interferon Beta-1a (Avonex) in Multiple Sclerosis (Lead Investigator)
50. An Open-Label, Randomized, Multi-Center, Comparative, Parallel Group Study Of Rebif 44 Mcg Administered Once Per Week By Intramuscular Injection In The Treatment Of Relapsing -- Remitting Multiple Sclerosis (Principal Investigator)
51. An Open-Label, Randomized, Multi-Center, Comparative Parallel Group Study of Rebif Compared with Avonex in Relapsing-Remitting Multiple Sclerosis (Principal Investigator)
52. Characterization of Human Schwann Cell Lines – In Vitro Safety and Viability Studies (Co- Investigator)
53. Phase I Trial of Autologous Schwann Cell Transplantation in MS as a Myelin Repair Strategy in MS Patients (Lead Investigator)
54. An Open-Label, Single-Arm, Cross-over, Frequent MRI Study of Simvastatin as a Therapy for Multiple Sclerosis (Lead Investigator)
55. A Multi-National, Multi-Center, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Tolerability, and Safety of Glatiramer Acetate for Injection in Primary Progressive Multiple Sclerosis Patients (Principal Investigator)
56. Randomized, Double Blind, Placebo-Controlled Study to Compare the Effects of Different Dose Regimens of IGIV-Chromatography (IGIV-C), 10% Treatment on Relapsed Rater in Patients with Multiple Sclerosis (Principal Investigator)
57. An Open-Label Safety Extension Study Of Avonex (Interferon Beta-1a Treatment In Subjects Who Completed Biogen Studies C95-812, C96-823, Or C97-830 (Principal Investigator)
58. A Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Efficacy of Avonex in the Treatment of Secondary Progressive Multiple Sclerosis (Principal Investigator)
59. An Open-Label, Randomized, Multi-Center, Comparative, Parallel Group Study of Rebif 44 mcg Administered Three Times Per Week by Subcutaneous Injection, Compared with Avonex 30 mcg Administered Once Per Week by Intramuscular Injection in the Treatment of Relapsing-Remitting Multiple Sclerosis (Principal Investigator)
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60. A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Safety, Tolerability And Dose Evaluation Study of Intravenous Antegren (Natalizumab) At Two Dose Levels Using Magnetic Resonance Imaging In Subjects With Multiple Sclerosis (Principal Investigator)
61. A Multi-National, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy, Tolerability, And Safety Of Two Doses (5 Mg And 50 Mg) Of Glatiramer Acetate Orally Administered In Relapsing Remitting Multiple Sclerosis Patient (Principal Investigator)
62. A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Study Comparing The Safety, Tolerance And Efficacy Of RTX (Resiniferatoxin) Topical Solution In Patients With Detrusor Hyperreflexia (Investigator)
63. Performance Scale V alidation Study (Principal Investigator)
64. Symptom Inventory Validation Study (Principal Investigator)
65. The Effects of Betaseron on Quality of Life in MS -A Q- TWiST Evaluation (Principal Investigator)
66. A Double-Blind, Placebo-Controlled, Multi-center Study of Oral Myelin (Myloral) in the Treatment of
Early Relapsing- Remitting MS (Principal Investigator)
67. A Phase II, Double-Masked, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Two
DosesofBetaseroninPatientswithSecondaryProgressiveMultipleSclerosis(Principal Investigator)
68. A Multi-Center, Open-Label, Long-term Study to Evaluate the Safety of Tizanidine for Spasticity Due
to MS (Principal Investigator)
69. A Double Blind, Placebo Controlled Trial of Total Lymphoidal Irradiation in Multiple Sclerosis
(Principal Investigator)
70. A Double Blind, Placebo Controlled Trial of Tizanidine as an Anti-Spastic Therapy in Multiple
Sclerosis (Principal Investigator)
71. A Double Blind, Placebo Controlled Phase II Trial of 4-AP in MS (Principal Investigator)
72. A Pharmacodynamic Study of Tizanidine in MS (Principal Investigator)
73. Open Trial of Tizanidine in Multiple Sclerosis (Principal Investigator)
74. A Double Blind, Placebo-Controlled, Dose-Determination, Safety, Tolerability and Efficacy Study of
Intravenous Antegren In Patients with Multiple Sclerosis During an Acute Exacerbation (Principal
Investigator)
75. A Phase II Study of Hu23F2G in Acute Exacerbations of Multiple Sclerosis (Principal Investigator)
76. An Open-Label Study to Assess the Long-Term Safety of Zanaflex (tizanidine HCL) in Patients Treated
with 28 to 36 mg/day (Principal Investigator)
77. An Open Label Dose Proportionality Study to Assess the Pharmacokinetics of Escalating Doses of
Fampridine (4-Aminopyridine) in Subjects with Multiple Sclerosis (Principal Investigator)
78. An Open-Label Protocol to Assess the Steady State Pharmacokinetics of orally Administered
Fampridine (4-Aminopyridine) in Subjects with Multiple Sclerosis (Principal Investigator)
79. An Open-Label, Safety and Pharmacokinetic Drug Interaction Study of Intravenous Antegren and
Intramuscular Interferon beta-1a in Subjects with Multiple Sclerosis (Principal Investigator)
80. The Prevalence of Neutralizing Antibodies in Patients Treated with Betaseron or Avonex (Principal
Investigator)
81. Factors Related to Non-Adherence to Treatment with Disease-Modifying Drugs in Multiple Sclerosis
(Co- Investigator)
82. A Double Blind, Placebo Controlled Multi-Center Trial of Copolymer-1 in Relapsing Multiple
Sclerosis (Principal Investigator)
83. Cost-Benefit And Cost-Effectiveness Analysis Of Interferon Beta-1a Therapies For Multiple Sclerosis
(Lead Investigator)
84. Randomized Multicenter Trial of Intravenous Natalizumab In Acute MS Relapses: Clinic and MRI
Effects (Lead Investigator)
85. CS 0777-A-U102, Daiichi Sankyo Pharma Development Vollmer (PI) This project assessed the
safety and tolerability of oral CS-0777 administered for 12 weeks in patients with MS.
86. Duloxetine in patients with central neuropathic pain. Lilly Research Laboratories Vollmer (PI)
This project assesses the efficacy of duloxetine 60 mg once daily (QD) compared with placebo on the
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reduction of pain severity as measured by the weekly mean of the daily 24-hour average pain scores
in patients with central neuropathic pain in MS.
87. HP 184: Nerispiroline, Sanofi Aventis US, Inc. Vollmer (PI)
This project assesses the activity of nerispirdine in imporving the ability to walk in persons with MS.
88. Consortium of Multiple Sclerosis Centers, NARCOMS Vollmer (PI)
The project is directed toward continuing the NARCOMS registry for persons with MS.
89. IPX056-B09-01, Impax V ollmer (PI)
A study with IPX056 in subjects with spasticity associated with multiple sclerosis
90. MS-LAQ, TEVA Neuroscience (BRAVO) Vollmer (PI)
This project assesses the efficacy, safety, and tolerability of laquinimod over placebo in a double-blind design and of a reference arm of Interferon β-1a (Avonex®) in a rater-blinded design and to perform a comparative benefit/risk assessment between oral laquinimod and injectable Interferon β-1a (Avonex®).
91. Disability-Specific Symptom Inventory Short Forms to Improve MS Outcome Assessment Vollmer (co-investigator)
Department of Defense, U.S. Army Medical Research Acquisition Activity (subcontract to DeltaQuest
Foundation, Inc)
92. ELND002-MS103, Elan Pharm V ollmer (PI)
To determine the safety and tolerability of ELND002 including the identification of dose-limiting
toxicity (ies) and determination of the maximum tolerated dose in patients with multiple sclerosis.
93. CAMMS32400507, Genzyme V ollmer (PI)
This project compares two annual cycles of IV low-and-high-dose Alemtuzumab to three-times weekly subcutaneous interferon beta 1a (Rebif) in patients with relapsing remitting multiple sclerosis
13. Bibliography—peer reviewed journal articles
1. Barbour RV DS, Vollmer TL, Harris JD. Pyrolysis of Utah tar sands - Products and Kinetics. Fuels. 1977;56:359-366.
2. Vollmer TL, Conley FK. Effect of cyclophosphamide on survival of mice and incidence of metastatic tumor following intravenous and intracardial inoculation of tumor cells. Cancer Res. Sep 1984;44(9):3902-3906.
3. Vollmer TL, Waldor MK, Steinman L, Conley FK. Depletion of T-4+ lymphocytes with monoclonal antibody reactivates toxoplasmosis in the central nervous system: a model of superinfection in AIDS. J Immunol. Jun 1 1987;138(11):3737-3741.
4. Redmond DE Jr SD, Naftolin F, Roth R, Bunney BS, Leranth C, Robbins R, Kier L, Vollmer TL, Levine RJ, Genel M, Zonana H. Ethics of Research Using Human Fedal Tissue. New England Journal of Medicine. 1989;321:1609.
5. Redmond DE, Jr., Leranth C, Spencer DD, Robbins R, Vollmer T, Kim JH, Roth RH, Dwork AJ, Naftolin F. Fetal neural graft survival. Lancet. Sep 29 1990;336(8718):820-822.
6. Vollmer TL, Brass LM, Waxman SG. Lhermitte's sign in a patient with herpes zoster. J Neurol Sci. Dec 1991;106(2):153-157.
7. Rice CL, Vollmer TL, Bigland-Ritchie B. Neuromuscular responses of patients with multiple sclerosis. Muscle Nerve. Oct 1992;15(10):1123-1132.
8. Spencer DD, Robbins RJ, Naftolin F, Marek KL, Vollmer T, Leranth C, Roth RH, Price LH, Gjedde A, Bunney BS, et al. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. N Engl J Med. Nov 26 1992;327(22):1541-1548.
9. Goldstein JM, Azizi SA, Booss J, Vollmer TL. Human immunodeficiency virus-associated motor axonal polyradiculoneuropathy. Arch Neurol. Dec 1993;50(12):1316-1319.
10. Redmond DE, Jr., Robbins RJ, Naftolin F, Marek KL, Vollmer TL, Leranth C, Roth RH, Price LH, Gjedde A, Bunney BS, et al. Cellular replacement of dopamine deficit in Parkinson's disease using
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human fetal mesencephalic tissue: preliminary results in four patients. Res Publ Assoc Res Nerv Ment
Dis. 1993;71:325-359.
11. Vollmer TL, Guarnaccia J, Harrington W, Pacia SV, Petroff OA. Idiopathic granulomatous angiitis of
the central nervous system. Diagnostic challenges. Arch Neurol. Sep 1993;50(9):925-930.
12. Goldstein JM, Waxman SG, Vollmer TL, Lang B, Johnston I, Newsom-Davis J. Subacute cerebellar
degeneration and Lambert-Eaton myasthenic syndrome associated with antibodies to voltage-gated calcium channels: differential effect of immunosuppressive therapy on central and peripheral defects. J Neurol Neurosurg Psychiatry. Sep 1994;57(9):1138-1139.
13. Miller A BD, Ritvo P, Stuart W, Vollmer T. The neurologist's perspective: what do we know and where do we go? Journal of Neurorehabilitation. 1994;8:105-111.
14. Smith C, Birnbaum G, Carter JL, Greenstein J, Lublin FD, Baumel B, Hsu CY, Murphy F, Reader AT, Schapiro RT, Sibley WA, Stazio A, Trotter JL, Vollmer TL, Walshe TM. Tizanidine treatment of spasticity caused by multiple sclerosis: results of a double-blind, placebo-controlled trial. US Tizanidine Study Group. Neurology. Nov 1994;44(11 Suppl 9):S34-42; discussion S42-33.
15. Weinberg DA, Lesser RL, Vollmer TL. Ocular myasthenia: a protean disorder. Surv Ophthalmol. Nov- Dec 1994;39(3):169-210.
16. Coulthard-Morris L, Vollmer T. Multiple sclerosis fatigue: classification and treatmetn options. Multiple Sclerosis. 1995;2:2-6.
17. Johnson KP, Brooks BR, Cohen JA, Ford CC, Goldstein J, Lisak RP, Myers LW, Panitch HS, Rose JW, Schiffer RB, Vollmer TL, Weiner LP, Wolinsky JS. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group. Neurology. Jul 1995;45(7):1268-1276.
18. Sass KJ, Buchanan CP, Westerveld M, Marek KL, Farhi A, Robbins RJ, Naftolin F, Vollmer TL, Leranth C, Roth RH, et al. General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson's disease. Arch Neurol. Jul 1995;52(7):680-686.
19. Vollmer TL. A neurologist's perspective on enhanced MRI of multiple sclerosis. MRI Perspectives. 1995;2:1-3.
20. Vollmer TL, Gaiser C, Dell'Oca RL, Porteus M, Steinman L, Stevens DA. Coccidioidal antigen reactive CD4+ T-lymphocytes in the cerebrospinal fluid in coccidioides immitis meningitis. J Med Vet Mycol. Jan-Feb 1995;33(1):43-48.
21. Maravilla KR, Vollmer TL. The current view of MRI in multiple sclerosis. MRI Perspectives. 1996;3:1-3.
22. Vollmer T. Multiple sclerosis: new approaches to immunotherapy. The Neuroscientist. 1996;2:127- 136.
23. Cook SD, Devereux C, Troiano R, Wolansky L, Guarnaccia J, Haffty B, Bansil S, Goldstein J, Sheffet A, Zito G, Jotkowitz A, Boos J, Dowling P, Rohowsky-Kochan C, Volmer T. Modified total lymphoid irradiation and low dose corticosteroids in progressive multiple sclerosis. J Neurol Sci. Nov 25 1997;152(2):172-181.
24. Nance PW, Sheremata WA, Lynch SG, Vollmer T, Hudson S, Francis GS, O'Connor P, Cohen JA, Schapiro RT, Whitham R, Mass MK, Lindsey JW, Shellenberger K. Relationship of the antispasticity effect of tizanidine to plasma concentration in patients with multiple sclerosis. Arch Neurol. Jun 1997;54(6):731-736.
25. Schwartz CE, Coulthard-Morris L, Cole B, Vollmer T. The quality-of-life effects of interferon beta-1b in multiple sclerosis. An extended Q-TWiST analysis. Arch Neurol. Dec 1997;54(12):1475-1480.
26. Johnson KP, Brooks BR, Cohen JA, Ford CC, Goldstein J, Lisak RP, Myers LW, Panitch HS, Rose JW, Schiffer RB, Vollmer T, Weiner LP, Wolinsky JS. Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group. Neurology. Mar 1998;50(3):701-708.
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27. Schwartz CE, Vollmer T, Lee H. Reliability and validity of two self-report measures of impairment and disability for MS. North American Research Consortium on Multiple Sclerosis Outcomes Study Group. Neurology. Jan 1 1999;52(1):63-70.
28. Sheremata WA, Vollmer TL, Stone LA, Willmer-Hulme AJ, Koller M. A safety and pharmacokinetic study of intravenous natalizumab in patients with MS. Neurology. Mar 23 1999;52(5):1072-1074.
29. Vollmer TL NW, Stanton S, Hadjimichael O. The NARCOMS patient registry: a resource for investigators. International Journal of MS Care. 1999;1:12-15.
30. Johnson KP, Brooks BR, Ford CC, Goodman A, Guarnaccia J, Lisak RP, Myers LW, Panitch HS, Pruitt A, Rose JW, Kachuck N, Wolinsky JS. Sustained clinical benefits of glatiramer acetate in relapsing multiple sclerosis patients observed for 6 years. Copolymer 1 Multiple Sclerosis Study Group (including Vollmer TL). Mult Scler. Aug 2000;6(4):255-266.
31. Minagar A SW, Vollmer TL, Willmer-Hulme AJ, Koller M. Reduction of relapses in multiple sclerosis after anti-alpha4 integrin antibody (natalizumab). International Journal of MS Care. 2000;2(1):1-6.
32. Vollmer TL. Use of MRI technology in determining prognosis and tracking therapeutic benefit in multiple sclerosis. International Journal of MS Care. 2000;2(2).
33. Fraser C, Hadjimichael O, Vollmer T. Predictors of adherence to Copaxone therapy in individuals with relapsing-remitting multiple sclerosis. J Neurosci Nurs. Oct 2001;33(5):231-239.
34. Kohama I, Lankford KL, Preiningerova J, White FA, Vollmer TL, Kocsis JD. Transplantation of cryopreserved adult human Schwann cells enhances axonal conduction in demyelinated spinal cord. J Neurosci. Feb 1 2001;21(3):944-950.
35. Goodman AD BA, Cohen JA, Cross AH, Katz M, Rizzo MA, Vollmer TL. Placebo-controlled double- blinded dose ranging study of fampridine-SR in multiple sclerosis. Multiple Sclerosis Clinical and Laboratory Research. September 2002 2002;8(1:S97):308.
36. Markovic-Plese S PA, Cortez A, Vollmer TL. Therapeutic potential of statins in relapsing-remitting multiple sclerosis. Mutliple Sclerosis Clinical and Laboratory Research. September 2002 2002;8(1:S127):340.
37. Marrie R CJ, Hadjimichael O, Vollmer TL. Use of alternative providers in multiple sclerosis. Multiple Sclerosis Clinical and Laboratory Research. September, 2002 2002;8(1):63.
38. Preiningerova J DZ, Cannistraci C, Sun H, Vollmer TL. Computer assisted volumetric analysis of gadolinium enhancement in multiple sclerosis. Mutliple Sclerosis Clinical and Laboratory Research. September, 2002 2002;8(1:S97):245.
39. Rizzo M HO, Buenconsejo J, Preiningerova J, Vollmer TL. Spasticity in MS patients in the NARCOMS registry: prevalence, severity and treatmetn patterns using oral agens and/or intrathecal baclofen. Multiple Sclerosis Clinical and Laboratory Research. September, 2002 2002;8(1:S80):191.
40. Vollmer T. (Guest Editor) Introduction: A single topic issue on multiple sclerosis. J of Rehabil Res Dev. 2002;39(2).
41. Vollmer TL, Hadjimichael O, J. B. Quality of life and cost of illness in mitoxantrone treated multiple sclerosis patients. Multiple Sclerosis Clinical and Laboratory Research. September, 2002 2002;8(1:s78):185.
42. Vollmer TL, Preiningerova J, Markovic-Plese S, Rizzo M, Cutter G. A phase IIB study of oral interferon beta-1a at two doses in relapsing remitting multiple sclerosis using MRI, clinical and immunological measures. Multiple Sclerosis Clinical and Laboratory Research. September, 2002 2002;8(1:S71):163.
43. Vollmer TL, Hadjimichael O, Preiningerova J, Ni W, Buenconsejo J. Disability and treatment patterns of multiple sclerosis patients in United States: a comparison of veterans and nonveterans. J Rehabil Res Dev. Mar-Apr 2002;39(2):163-174.
44. Fraser C, Hadjimichael O, Vollmer T. Predictors of adherence to glatiramer acetate therapy in individuals with self-reported progressive forms of multiple sclerosis. J Neurosci Nurs. Jun 2003;35(3):163-170.
45. Marrie RA, Hadjimichael O, Vollmer T. Predictors of alternative medicine use by multiple sclerosis patients. Mult Scler. Oct 2003;9(5):461-466.
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46. The Transverse Myelitis Consortium Working Group (including Vollmer T). Proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology. Feb 25 2003;60(4):730-731; author reply 730-731.
47. Fraser C, Morgante L, Hadjimichael O, Vollmer T. A prospective study of adherence to glatiramer acetate in individuals with multiple sclerosis. J Neurosci Nurs. Jun 2004;36(3):120-129.
48. O'Connor PW, Goodman A, Willmer-Hulme AJ, Libonati MA, Metz L, Murray RS, Sheremata WA, Vollmer TL, Stone LA. Randomized multicenter trial of natalizumab in acute MS relapses: clinical and MRI effects. Neurology. Jun 8 2004;62(11):2038-2043.
49. Rizzo MA, Hadjimichael OC, Preiningerova J, Vollmer TL. Prevalence and treatment of spasticity reported by multiple sclerosis patients. Mult Scler. Oct 2004;10(5):589-595.
50. Vollmer T, Key L, Durkalski V, Tyor W, Corboy J, Markovic-Plese S, Preiningerova J, Rizzo M, Singh I. Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet. May 15 2004;363(9421):1607-1608.
51. Vollmer TL SI. Author's reply for statins in multiple sclerosis. The Lancet. July 2004 2004;364:412- 413.
52. Vollmer TL, Phillips JT, Goodman AD, Agius MA, Libonati MA, Giacchino JL, Grundy JS. An open- label safety and drug interaction study of natalizumab (Antegren) in combination with interferon-beta (Avonex) in patients with multiple sclerosis. Mult Scler. Oct 2004;10(5):511-520.
53. Ding Z, Preiningerova J, Cannistraci CJ, Vollmer TL, Gore JC, Anderson AW. Quantification of multiple sclerosis lesion load and brain tissue volumetry using multiparameter MRI: methodology and reproducibility. Magn Reson Imaging. Apr 2005;23(3):445-452.
54. Hadjimichael O, Cutter G, Tyry T, Vollmer T. Are untreated MS patients representative of historical controls or what do they say about trial recruitment? Neurology. 2005;March 2005(Suppl 1):S36.005.
55. Khan M, Vollmer T, Singh A. Lovastatin augments the survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. Mult Scler. September 2005 2005;11(Supplement 1):P212.
56. Liu R LA, Bai X, Jee Y, Price M. Campagnolo D, Christadoss P, Vollmer T, Van Kaer L, Shi F. Cooperation of iNKT cells and CD4+CD25+ treg cells in the prevention of autoimmune myasthenia. Neurology. 2006 March 14;66((5 Suppl 2)):A306.
57. Lo AC, Hadjimichael O, Vollmer TL. Treatment patterns of multiple sclerosis patients: a comparison of veterans and non-veterans using the NARCOMS registry. Mult Scler. Feb 2005;11(1):33-40.
58. Marrie RA, Cutter G, Tyry T, Hadjimichael O, Campagnolo D, Vollmer T. Validation of the NARCOMS registry: fatigue assessment. Mult Scler. Oct 2005;11(5):583-584.
59. Marrie RA, Cutter G, Tyry T, Hadjimichael O, Campagnolo D, Vollmer T. Changes in the ascertainment of multiple sclerosis. Neurology. Oct 11 2005;65(7):1066-1070.
60. Marrie RA, Cutter G, Tyry T, Hadjimichael O, Vollmer T. Validation of the NARCOMS Registry: pain assessment. Mult Scler. Jun 2005;11(3):338-342.
61. Paintlia AS, Paintlia MK, Khan M, Vollmer T, Singh AK, Singh I. HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. FASEB J. Sep 2005;19(11):1407-1421.
62. Sheremata WA, Minagar A, Alexander JS, Vollmer T. The role of alpha-4 integrin in the aetiology of multiple sclerosis: current knowledge and therapeutic implications. CNS Drugs. 2005;19(11):909-922.
63. Vollmer TL, Liu R, Price M, Rhodes S, La Cava A, Shi FD. Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen. J Immunol. Mar 1 2005;174(5):2696- 2701.
64. Kasper LH, Everitt D, Leist TP, Ryan KA, Mascelli MA, Johnson K, Raychaudhuri A, Vollmer T. A phase I trial of an interleukin-12/23 monoclonal antibody in relapsing multiple sclerosis. Curr Med Res Opin. Sep 2006;22(9):1671-1678.
65. Liu R, Van Kaer L, La Cava A, Price M, Campagnolo DI, Collins M, Young DA, Vollmer TL, Shi FD. Autoreactive T cells mediate NK cell degeneration in autoimmune disease. J Immunol. May 1 2006;176(9):5247-5254.
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66. Marrie R, Cutter G, Tyry T, Vollmer T, Campagnolo D. NARCOMS validation study. Neurology. 2006;66(5 Suppl 2):A226.
67. Marrie RA, Cutter G, Tyry T, Vollmer T, Campagnolo D. Does multiple sclerosis-associated disability differ between races? Neurology. Apr 25 2006;66(8):1235-1240.
68. Panitch HS, Thisted RA, Smith RA, Wynn DR, Wymer JP, Achiron A, Vollmer TL, Mandler RN, Dietrich DW, Fletcher M, Pope LE, Berg JE, Miller A. Randomized, controlled trial of dextromethorphan/quinidine for pseudobulbar affect in multiple sclerosis. Ann Neurol. May 2006;59(5):780-787.
69. Peng X, Jin J, Giri S, Montes M, Sujkowski D, Tang Y, Smrtka J, Vollmer T, Singh I, Markovic-Plese S. Immunomodulatory effects of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors, potential therapy for relapsing remitting multiple sclerosis. J Neuroimmunol. Sep 2006;178(1-2):130- 139.
70. Tyor WR IS, Vollmer T, Key L, Corboy J, Markovic-Plese S, Preningerova J, Durkalski V, Rizzo M. The use of statins in multiple sclerosis. International Journal of MS Care. 2006;8:10-12.
71. Jee Y LR, Bai X, Campagnolo D, Shi F, Vollmer T. Do Th2 cells mediate the effects of glatiramer acetate in experimental autoimmune encephalomyelitis? Int Immunol. 2006 April;18(4):537-544.
72. Vollmer T, LaPierre Y, Weiner L, Oger J, Bar-Or A, Arnold D, Campagnolo D, Barkas W, Antel J, Kachuck N. Garren H, Gianettttoni J, Steinman L, Valone F. Phase I/II trial of MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin for treatment of multiple sclerosis. Neurology. 2006 Mar 14;66((5 Suppl 2)):A306.
73. Liu R, La Cava A, Bai XF, Jee Y, Price M, Campagnolo DI, Christadoss P, Vollmer TL, Van Kaer L, Shi FD. Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in the prevention of autoimmune myasthenia. J Immunol. Dec 15 2005;175(12):7898-7904.
74. Paintlia A PM, Singh A, Vollmer T, Singh I. Combination therapy with Lovastatin and 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside: approach for neuroprotection and inhibition of neurodegeneration in multiple sclerosis. Neurology. 2006 March 14;66((5 Suppl 2)):A303.
75. Coyle PK, Halper J, Johnson KP, Kalb R, Lublin F, Marrow T, Panitch H, Rabouls T, Vollmer T. Relapses matter: the costs & consequences of multiple sclerosis relapses. J Neurol Sci. May 15 2007;256 Suppl 1:S1-4.
76. Goodman AD, Cohen JA, Cross A, Vollmer T, Rizzo M, Cohen R, Marinucci L, Blight AR. Fampridine-SR in multiple sclerosis: a randomized, double-blind, placebo-controlled, dose-ranging study. Mult Scler. Apr 2007;13(3):357-368.
77. Hadjimichael O, Kerns RD, Rizzo MA, Cutter G, Vollmer T. Persistent pain and uncomfortable sensations in persons with multiple sclerosis. Pain. Jan 2007;127(1-2):35-41.
78. Marrie RA, Cutter G, Tyry T, Campagnolo D, Vollmer T. Validation of the NARCOMS registry: diagnosis. Mult Scler. Jul 2007;13(6):770-775.
79. Marrie RA, Cutter G, Tyry T, Vollmer T, Campagnolo D. Disparities in the management of multiple sclerosis-related bladder symptoms. Neurology. Jun 5 2007;68(23):1971-1978.
80. Schwartz EI, Smilenov LB, Price MA, Osredkar T, Baker RA, Ghosh S, Shi FD, Vollmer TL, Lencinas A, Stearns DM, Gorospe M, Kruman, II. Cell cycle activation in postmitotic neurons is essential for DNA repair. Cell Cycle. Feb 1 2007;6(3):318-329.
81. Vollmer T. The natural history of relapses in multiple sclerosis. J Neurol Sci. May 15 2007;256 Suppl 1:S5-13.
82. Arnold DL, Campagnolo D, Panitch H, Bar-Or A, Dunn J, Freedman MS, Gazda SK, Vollmer T. Glatiramer acetate after mitoxantrone induction improves MRI markers of lesion volume and permanent tissue injury in MS. J Neurol. Oct 2008;255(10):1473-1478.
83. Bomprezzi R SM, Vollmer TL. Acute axonal polyneuropathy combined with acute disseminated encephalomyelitis: case report. Barrow Quarlery. 2008;24(2):21-23.
84. Devitt M, Foley FW, Miller RJ, Zemon V, Halper J, Campagnolo D, Vollmer T. Use of single screening question from NARCOMS to detect severe depression in multiple sclerosis. International Journal of MS Care. 2008;10(1):11-13.
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85. Hadjimichael O, Vollmer T, Oleen-Burkey M. Fatigue characteristics in multiple sclerosis: the North American Research Committee on Multiple Sclerosis (NARCOMS) survey. Health Qual Life Outcomes. 2008;6:100.
86. Hauser SL, Waubant E, Arnold DL, Vollmer TL, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med. Feb 14 2008;358(7):676-688.
87. Julian LJ, Vella L, Vollmer T, Hadjimichael O, Mohr DC. Employment in multiple sclerosis. Exiting and re-entering the work force. J Neurol. Sep 2008;255(9):1354-1360.
88. Marrie R, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. Comorbidity, socioeconomic status and multiple sclerosis. Mult Scler. Sep 2008;14(8):1091-1098.
89. Marrie RA, Cutter G, Tyry T, Vollmer T, Campagnolo D. Validation of the NARCOMS registry: depression assessment. International Journal of MS Care. 2008;10(3):84-84.
90. Vollmer T, Panitch H, Bar-Or A, Dunn J, Freedman MS, Gazda SK, Campagnolo D, Deutsch F, Arnold DL. Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis. Mult Scler. Jun 2008;14(5):663-670.
91. Zhao CB, Coons SW, Cui M, Shi FD, Vollmer TL, Ma CY, Kuniyoshi SM, Shi J. A new EAE model of brain demyelination induced by intracerebroventricular pertussis toxin. Biochem Biophys Res Commun. May 23 2008;370(1):16-21.
92. Bar-Or A, Oger J, Gibbs E, Niino M, Aziz T, Renoux C, Alatab S, Shi FD, Campagnolo D, Jalili F, Rhodes S, Yamashita T, Fan B, Freedman MS, Panitch H, Arnold DL, Vollmer T. Serial combination therapy: is immune modulation in multiple sclerosis enhanced by initial immune suppression? Mult Scler. Aug 2009;15(8):959-964.
93. Buchanan RJ, Chakravorty BJ, Tyry T, Hatcher W, Vollmer T. Age-related comparisons of people with multiple sclerosis: demographic, disease, and treatment characteristics. NeuroRehabilitation. 2009;25(4):271-278.
94. Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH. Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial. Ann Neurol. Oct 2009;66(4):460-471.
95. Marrie R, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. High frequency of adverse health behaviors in multiple sclerosis. Mult Scler. Jan 2009;15(1):105-113.
96. Marrie RA CG, Tyry T, Campagnolo D, Vollmer T. Effect of physical comorbidities on risk of depression in multiple sclerosis. International Journal of MS Care. 2009;11(4):161-165.
97. Marrie RA, Cutter G, Tyry T, Vollmer T. Bladder care for veterans with MS differ by treatment location. International Journal of MS sCare. 2009;11:91-97.
98. Marrie RA, Cutter G, Tyry T, Campagnolo D, Vollmer T. Smoking status over two years in patients with multiple sclerosis. Neuroepidemiology. 2009;32(1):72-79.
99. Marrie RA, Cutter G, Tyry T, Vollmer T. A cross-sectional study of bone health in multiple sclerosis. Neurology. Oct 27 2009;73(17):1394-1398.
100. Marrie RA, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. Comorbidity delays diagnosis and increases disability at diagnosis in MS. Neurology. Jan 13 2009;72(2):117-124.
101. Marrie RA, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer, TL . The burden of mental comorbidity in multiple sclerosis: frequent, underdiagnosed, and undertreated. Mult Scler. Mar 2009;15(3):385-392.
102. Motl RW, Schwartz CE, Vollmer T. Continued validation of the Symptom Inventory in multiple sclerosis. J Neurol Sci. Oct 15 2009;285(1-2):134-136.
103. Shi FD, Piao WH, Kuo YP, Campagnolo DI, Vollmer TL, Lukas RJ. Nicotinic attenuation of central nervous system inflammation and autoimmunity. J Immunol. Feb 1 2009;182(3):1730-1739.
104. Tu JL, Zhao CB, Vollmer T, Coons S, Lin HJ, Marsh S, Treiman DM, Shi J. APOE 4 polymorphism
results in early cognitive deficits in an EAE model. Biochem Biophys Res Commun. Jul 10 2009;384(4):466-470.
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105. Vollmer T, Blight AR, Henney HR, 3rd. Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, follow-up study. Clin Ther. Oct 2009;31(10):2215-2223.
106. Vollmer T, Henney HR, 3rd. Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: a Phase I-II, open-label trial. Clin Ther. Oct 2009;31(10):2206-2214.
107. Buchanan RJ, Minden SL, Chakrovorty BJ, Hatcher W. Tyry T, Vollmer T. A pilot study of young adults with multiple sclerosis: Demographic, disease, treatment and psychosocial characteristics. Disabil Health J Oct: 3(4):262-70. Epub 2009 Nov 26.
108. Bandari DS, Vollmer TL, Khatri BO, Tyry T. Assessing quality of life in patiaents with multiple sclerosis. International Journal of MS Care. 2010;12(1):34-40.
109. Bomprezzi R, Pati S, Chansakul C, Vollmer T. A case of neurosarcoidosis successfully treated with rituximab. Neurology. Aug 10 2010;75(6):568-570.
110. Kala M, Rhodes SN, Piao WH, Shi FD, Campagnolo DI, Vollmer TL. B cells from glatiramer acetate- treated mice suppress experimental autoimmune encephalomyelitis. Exp Neurol. Jan 2010;221(1):136- 145.
111. Marrie RA, Horwitz RI, Cutter G, Tyry T, Vollmer T. Association between comorbidity and clinical characteristics of MS. Acta Neurol Scand. Sep 29 2010 124:2 135-41.
112. Marrie RA, Rudick R, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology. Mar 30 2010;74(13):1041-1047.
113. Salter AR, Cutter GR, Tyry T, Marrie RA, Vollmer T. Impact of loss of mobility on instrumental activities of daily living and socioeconomic status in patients with MS. Curr Med Res Opin. Feb 2010;26(2):493-500.
114. Vollmer T, Stewart T, Baxter N. Mitoxantrone and cytotoxic drugs' mechanisms of action. Neurology. Jan 5 2010;74 Suppl 1:S41-46.
115. Wynn D, Kaufman M, Montalban X, Vollmer T, Simon J, Elkins J, O'Neill G, Neyer L, Sheridan J, Wang C, Fong A, Rose JW. Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta. Lancet Neurol. Apr 2010;9(4):381-390.
116. Goodman AD, Brown TR, Edward KR, Krupp LB, Schapiro RT, Cohen R, Marinucci LN, Blight AR on behalf of the MSF204 Investigators (Vollmer TL). A phase 3 trial of extended release oral dalfampridine in multiple sclerosis. Ann Neurol Oct 2010;68:494-502
117. Chang J, Campagnolo D, Vollmer TL, Bomprezzi R. Demyelinating disease and polyvalent human papilloma virus vaccination. J Neurol Neurosurg Psychiatry. Published online Oct 9 2010. Doi: 10.1136/jnnp.2010.214924.
118. Buchanan RJ, Zuniga MA, Carrillo-Zuniga G, Chakrovorty BJ, Tyry T, Moreau RL, Huang C, Vollmer T. Comparisons of Latinos, African Americans and Caucasians with multiple sclerosis. Ethnicity and Disease 2010;20 autumn:451-457.
119. Marrie RA, Rudick R, Norwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology 2010 74:13 1041- 7
120. Marrie RA, Horwitz R, Cutter G, Tyry T, Vollmer T. Smokers with MS are more likely to report comorbid autoimmune diseases. Neuroepidemiology 2011;36:85-90 (doi: 10.1159/000323948)
121. Bomprezzi R, Postevka E, Campagnolo D, Vollmer TL. A review of cases of neuromyelitis optica. Neurologist 2011 March;17(2):98-104.
122. Vollmer T, Wynn D, Alam S, Valdes J. A phase 2, 24-week, randomized, placebo-controlled, double- blind study examining the efficacy and safety of an anti-interleukin-12 and-23 monoclonal antibody in patients with relasping-remitting or secondary-progressive multiple sclersois. 2011 Multiple Sclerosis Journal February17(2) 181--191 .
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123. Miravalle A, Hendin B, Vollmer TL, Mrinalini K. Glatiramer acetate in the reduction of relapse frequency in multiple sclerosis. Clinical Medicine Insights: Therapeutics. 2011:3 151—158
124. Motl RW, McAuley E, Wynn D, Vollmer T. Lifestyle physical activity and walking impairment over time in relapsing-remitting multiple sclerosis: results from a panel study. Am J. Phys. Med. Rehabil May 2011(90;5);372—379
125. Hao J, Campagnolo D. Liu R, Piao W, Shi S, Hu B, Xiang R, Zhou Q, Vollmer T, VanKaer L, LaCava A, Shi FD. Interleukin-2/InterleukinL 2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation. Published online 18 MAR 2011 Annals of Neurology,
69: n/a. doi: 10. 1002/ana.22339
126. Schwartz CE, Sprangers MA, Oort FJ, Ahmed S, Bode R, Li Y, Vollmer T. Response shift in patients with multiple sclerosis: an application of three statistical techniques. Qual Life Res, 2011 20:10 1561- 72.
127. Buchanan RJ, Zuniga MA, Carrillo-Zuniga G, Chakravorty BJ, Tyry T, Moreau RL, Vollmer T. A pilot study of latinos with multiple sclerosis: demographic, disease, metnal health and psychosocial characteristics. Journal of Social Work in Disability & Rehabililtation, Nov 30, 2011, 10:4, 211-231
128. Shi J, Tu JL, Gale, SD, Baxter L, Vollmer TL, Campagnolo DI, Tyry TM, Zhuang Y, Kuniyoshi SM. APOE epsilon4 is associated with exacerbation of cognitive decline in patients with multiple sclerosis. Cogn Behav Neurol 2011 24:3 128—33.
129. Bomprezzi, R, Schafer R, Reese V, Misra A, Vollmer TL, Kala M. Glatiramer acetate-specific antibody itres in patients with relapsing/remitting multiple sclerosis and in experimental autoimmunte encephalitis. Scan J. Immunol. 2011 74:3 219-26.
13.1 Bibliography-Peer Reviewed Publications—In press/accepted for publication
1. 2. 3. 4.
5. 6.
7. 8.
9.
Smith R, Trisolini M, Mauskopf J, Eckert B, Vollmer T. The side effects and mode of administration of disease-modifying therapies on EQ-5D index scores. 2009 Multiple Sclerosis (in press)
Kala M, Bomprezzi R, Schafer R, Resse V, Campagnolo D, Vollmer T. Glatiramer specific antibody titers do not correlate with clinical outcomes of multiple sclerosis. 2010 (accepted)
Smith KW, Trisolini M, Mauskopf J, Eckert B, Vollmer T. Impact of treatment burden associated with injected disease-modifying therapies on health utility in multiple sclerosis. 2010. (accepted) Yarden J. Schmidt H., Spector L, Fire E, Loud S, Dotan N, Venkatasan A, Frohman E, Sadiq S, Thrower B, Riskind P, Rackle MK, Vollmer TL, Kingel RP. gMS®ProEDSS blood tests based on anti-GAGA antibodies detects rapid relapsing remitting multiple sclerosis disability progression. 2010 (pending)
Moreau R, Salter AR, Tyry T, Marrie RA, Vollmer T, Cutter GR. Work absenteeism and mobility levels in people with multiple sclerosis. 2010 (pending)
Waubant E, Pelletier D, Mass M, Cohen J, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stuve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi P, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetski H, Ding L, Rosenberg E, ITN020AI Study Management team Spencer C, Zamvil SS. A randomized double-blind controlled study of Atorvastatin therapy in patients with clinically isolated syndrome: the STAyCIS study. (in progress)
Kala M, Miravalle A, Vollmer T. Recent advances in mechanism of action of glateramer acetate. 2011 Journal of Neuroimmunology (accepted-in press)
Schwartz CE, Bode RK, Vollmer TL. The symptom inventory disability-specific short forms for multiple sclerosis: Construct validity and responsiveness, and interpretation. Archives of Physical Medicine and Rehabilitation, 2012 (pending)
Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross AH, Bar-Or A, Vollmer TL, Racke MK, Stuve O, Schwid SR, Goodman AD, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Ikle D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C,
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10.
11. 12.
13.
13.2 1. 2. 3.
4. 5. 6. 7.
8.
9. 10.
13.3. 1.
2.
Zamvil SS. Randomized controlled trial of atorvastatin in clinically isolated syndrome: the STAyCIS Study. Accepted for publication in Neurology 2011.
Campbell J, McQueen RB, Miravalle A, Corboy J, Vollmer T, Nair K. Comparative effectiveness of early natalizumab treatment in JCV negative relapsing-remitting MS. Submitted to Neurology Jan. 2012
Schwartz, CE, Snook, E, Quaranto B, Benedict RHB, Rapkin BD, Vollmer T. Cognitive reserve and appraisal in multiple sclerosis. MS and Related Disorders under review March, 2012
Moberly J, Vollmer T et. al Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: Results from a 12-week, open-label pilot study in multiple sclerosis patients. Accepted for publication in J of Neuroimmunology, in press March, 2012
Schwartz CE, Bode RK, Vollmer T. The symptom inventory disability-specific short-forms for multiple sclerosis: Reliability and factor structure. Archivies of Physical Medicine and Rehabilitation, 2012 (in press)
Bibliography-- Book Chapters
Vollmer TL. Waxman SG. Multiple Sclerosis and Other Demyelinating Disorders. In Neurology. Ed. R. Rosenberg. Raven Press. 1991.
Vollmer TL. Waxman SG. Demyelinating Disorders of the Central Nervous System. In Neurologic Emergencies. Ed. WJ Weiner. JB Lippincott & Co. 1992.
Redmond DE. Robbins RJ. Raftolin F. Marek KL. Vollmer TL. Leranth C. Roth RH. Price LH. Gjedde A. Bunney BS. Sass KJ. Elsworth JD. Kier EL. Makuch R. Hoffer PB. Spencer DD. Cellular Replacement Strategy to Restore Dopamine Deficit In Parkinson's Disease Using Grafts of Fetal Mesencephalic Tissue: Preliminary Results In Four Patients. In Molecular and Cellular Approaches to the Treatment of Neurological Disease. Ed. S.G. Waxman. Raven Press. 1994.
Vollmer TL. Waxman SG. Demyelinating Disorders of the Central Nervous System. In Neurology. Ed. R. Rosenberg. Raven Press. 1997.
Vollmer TL P1-22 Multiple Sclerosis: The Disease and Its Diagnosis. In Multiple Sclerosis in Clinical Practice. Ed. S. van den Noort and N. Holland. Demos Medical Publishing. 1999.
Vollmer TL. Preiningerova J. Waxman SG. Multiple Sclerosis. In Encyclopedia of Life Sciences, http://www.els.net, London: Nature Publishing Group. 2002.
Okuda DT, Vollmer TL. Primary Angiitis of the Central Nervous System. MR Imaging in White Matter Diseases of the Brain and Spinal Cord (Medical Radiology/Diagnostic Imaging). Editors: M. Filippi, N DeStefano, V Dousset, and JC McGowan (2006).
Campagnolo D, Vollmer T, Shi F, Scott D, Williamson S. eMedicine Journal, January 9, 2006 ;7:1 (Sections 1 –12). Submitted.
Shi F, Campagnolo D, Vollmer T. Immune Therapy for Multiple Sclerosis: Altered Peptide Ligands and Statins. MS Handbook. Ed: S. Cook. Accepted.
Preiningerova J, Bomprezzi R, Vollmer T L, Waxman SG (June 2009) Multiple Sclerosis in: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. DOI:10,1002/9780470015902.a0000192.pub2.http://www.els.net
Bibliography—Abstracts and other presentations
Vollmer TL. Tausch G. Porteus M. Lim M. Steinman L. Antigen specific proliferation of T cells from the cerebrospinal fluid of patients with fungal meningitis. Presented at the 6th International Congress of Immunology, 1986. (In Abstracts from the 6th International Congress of Immunology,1986, p. 711.)
Young R. Vollmer TL. Farr K. Sena M. Genetic control of susceptibility to acute and persistent infection in trigeminal ganglia by herpes simplex virus. Presented at the American Academy of
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Neurology 38th Annual Meeting, New Orleans, LA, 1986. (Abstract published in Neurology, 36,
Suppl. 1, 1986, p. 222.)
3. Young R. Vollmer TL. Farr K. Sena M. Genetic control of susceptibility to acute and persistent
infection in trigeminal ganglia by herpes simplex virus. Presented at the American Academy of Neurology 38th Annual Meeting, New Orleans, LA, 1986. (Abstract published in Neurology, 36, Suppl. 1, 1986, p. 222.)
4. Gjedde A. Leger G. Guttman M. Kuwabara H. Diksic M. Spencer DD. Naftolin F. Robbins RJ. Roth RH. Bunney B. Fatigue in multple sclerosis patients. Presented at the 19th Annual Meeting of the Society for Neuroscience, Phoenix, AZ, 1989. (Abstract published in Society for Neuroscience Abstracts, 15, 1989, p. 932.)
5. Ellsworth JD. Redmond DE Jr. Spencer DD. Vollmer TL. Marek KL. Naftolin F. Robbins RJ. Leranth C. Kier EL. Bunney BS. Roth RH. CSF HVA in Parkinsonian patients after fetal mesencephalic tissue implants into caudate nucleus. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992, p. 283.)
6. Redmond DE Jr. Marek KL. Spencer DD. Natfolin F. Robbins RJ. Bunney BS. Leranth C. Vollmer TL. Fahri AE. Ashby AMC. Lawrence MS. Serrano CC. Levy LL. Kier EL. Elsworth JD. Roth RH. Changes in motor performance after unilateral caudate implantation of fetal mesencephalic tissue. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992, p. 198.)
7. Marek KL. Spencer DD. Naftolin F. Robbins RJ. Roth RH. Bunney BS. Leranth C. Vollmer TL. Fahri AE. Serrano CC. Levy L. Sass KJ. Price LH. Redmond DE Jr. Clinical effects of implantation of the caudate nucleus with fetal mesencephalic tissue in four Parkinsonian patients. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992, p. 197.)
8. Spencer DD. Naftolin F. Robbins RJ. Roth RH. Bunney BS. Leranth C. Vollmer TL. Price LH. Kier EL. Marek KL. Gjedde A. Fahri AE. Redmond DE Jr. Effects of human fetal tissue grafts in four Parkinsonian patients. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992, p. 197.)
9. Klotz KL. Goldstein JM. Booss J. Lee J. Vollmer TL. Trafficking of immune cells into CNS: Sequence of phenotypes. Presented at the American Academy of Neurology 4
10. Goldstein JM. Klotz K. Booss J. Vollmer TL. A mouse model of CNS inflammation: The role of adhesion molecules. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992. p. 325.)
11. Vollmer TL. Dalton J. Klotz K. Goldstein JM. Astrocyte-lymphocyte binding: The role of immune cytokines and ICAM-1. Presented at the American Academy of Neurology 44th Annual Meeting, San Diego, CA, 1992. (Abstract published in Neurology, 42, Suppl. 3, 1992, p. 158.)
12. Lee JH. Vollmer TL. Ransom BR. Extracellular pH and epileptiform activity in rat hippocampal slices. Presented at the 23rd Annual Meeting of the Society for Neuroscience, Washington, DC, 1993. (In Society for Neuroscience Abstracts, 19, Part 3, 1993, p. 1870.)
13. Vollmer TL. Shellenberger MK. U.S. Tizanidine MS Study Group. Efficacy and safety of tizanidine for reduction of spasticity in multiple sclerosis. Presented at the American Academy of Neurology 46th Annual Meeting, Washington, DC, 1994. (Abstract published in Neurology, 44, 1994, p. A375.)
14. Cook SD. Newark NJ. Bansil S. Boos J. Devereau C. Haffty B. Goldstein JM. Guarnaccia J. Rohowsky-Kochan C. Sheffet A. Troiano R. Vollmer TL. Wolansky L. Zito G. Total lymphoid irradiation (TLI) and Low-Dose Prednisone (LDP) in progressive multiple sclerosis (PMS). Presented at the American Academy of Neurology 47th Annual Meeting, Seattle, WA, 1995. (Abstract published in Neurology, 45, Suppl. 4, 1995, p. A417.)
15. Schwartz C. Vollmer TL. Zeng Q. North American Research Consortium on Multiple Sclerosis. New outcome measures for multiple sclerosis clinical research: The symptom inventory and the
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performance scales. Presented at the American Academy of Neurology 48th Annual Meeting, San
Francisco, CA, 1996. (Abstract published in Neurology, 46, Suppl. to #2, 1996, p. A321.)
16. Sheremata WA. Vollmer TL. Stone LA. Willmer-Hulme AJ. Koller ME. A placebo-controlled,
safety, tolerability, dose escalation, PK study of various doses of intravenous Antegren in patients with multiple sclerosis. Presented at the American Academy of Neurology 50th Annual Meeting, Minneapolis, MN, 1998. (Abstract published in Neurology, 50, Suppl. 4, 1998, pp. A63-A64.)
17. Bever CT Jr. Koller M. Hulme A. Walicke P. Vollmer TL. Sheremata W. Johnson K. Inter-rater variability in the scoring of the Scripps Neurological Rating Scale and the Expanded Disability Status Scale: Improvement with training. Presented at the 123rd Annual Meeting of the American Neurological Association, Montreal, Quebec, Canada, 1998. (Abstract published in the Program of the Annual Meeting, 1998.)
18. Vollmer TL. Safety and tolerability of glatiramer acetate for injection (formerly known as Copolymer-1) in the treatment of multiple sclerosis patients previously treated with interferon beta- 1b. Presented at the 123rd Annual Meeting of the American Neurological Association, Montreal, Quebec, Canada, 1998. (Abstract published in the Program of the Annual Meeting, 1998.)
19. Guarnaccia JB. Vollmer TL. Combination treatment regimens using interferon beta and immunosuppressive/ cytotoxic drugs in patients with multiple sclerosis. Presented at the 123rd Annual Meeting of the American Neurological Association, Montreal, Quebec, Canada, 1998. (Abstract published in the Program of the Annual Meeting, 1998, and in Annuals of Neurology, 44, 1998, p. W250.)
20. Sheremata WA. Minagar A. Hulme A. Koller M. Vollmer T. Reduction of relapses in multiple sclerosis after natalizumab (Antegren) treatment. Presented at the 123rd Annual Meeting of the American Neurological Association, Montreal, Quebec, Canada, 1998. (Abstract published in the Program of the Annual Meeting, 1998.)
21. Preiningerova J. Miyazaki T. Yu RK. Adelson K. Anderson A. Pukdaman N. Vollmer TL. The potential role of antibodies against glycosphinogolipids in axonal loss in multiple sclerosis. Presented at the American Academy of Neurology 51st Annual Meeting, Toronto, Ontario, Canada, 1999. (Abstract published in Neurology, 52, Suppl. 2, 1999, p. A399.)
22. Hadjimichael O. Vollmer TL. Adherence to injection therapy in multiple sclerosis: Patient survey. Presented at the American Academy of Neurology 51st Annual Meeting, Toronto, Ontario, Canada, 1999. (Abstract published in Neurology, 52, Suppl. 2, 1999, p. A549.)
23. Vollmer TL. Ni W. Hadjimichael O. Auld E. A study by the North American Research Consortium on Multiple Sclerosis (NARCOMS) of patients with multiple sclerosis in the Veterans Healthcare Administration (VHA) compared to the non-VHA population. Presented at the Rehabilitation In Multiple Sclerosis-Consortium of Multiple Sclerosis Centers (RIMS-CMSC) Joint Symposium, Basel, Switzerland, 1999. (Abstract published in Multiple Sclerosis, 5, Suppl. 1, 1999, p. S130.)
24. Vollmer TL. Ni W. Hadjimichael O. The North American Research Committee on Multiple Sclerosis Patient Registry: A progress report. Presented at the 15th Congress of the European Committee for Treatment and Research In Multiple Sclerosis / 4th Annual Meeting of America’s Committee for Treatment and Research In Multiple Sclerosis (ECTRIMS / ACTRIMS 99), Basel, Switzerland, 1999. (Abstract published in Multiple Sclerosis, 5, Suppl. 1, 1999, p. S74.)
25. Vollmer TL. Hadjimichael O. Ni W. The cause of non-adherence to disease-course altering therapies: A comparative study. Presented at the 15th Congress of the European Committee for Treatment and Research in Multiple Sclerosis/ 4th Annual Meeting of America’s Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS/ACTRIMS 99), Basel, Switzerland, 1999. (Abstract published in Multiple Sclerosis, 5, Suppl. 1, 1999, p. S97.)
26. Vollmer TL. Ni W. Hadjimichael O. Why are eligible patients with multiple sclerosis not on treatment with interferon beta or glatiramer acetate: Risk factors for non-treatment. Presented at the American Neurological Association 124th Annual Meeting, Seattle, WA, 1999. (Abstract published in Annuals of the 124th Annual Meeting of the American Neurological Association, 1999, p. 35.)
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27. Vollmer TL. Ni W. Hadjimichael O. Utilization patterns of immunological therapies among VA patients with multiple sclerosis. Presented at the American Neurological Association 124th Annual Meeting, Seattle, WA, 1999. (Abstract published in Annals of the 124th Annual Meeting of the American Neurological Association, October 1999, p. 51.)
28. Cook SD. Quiniess JR. Jotkowitz A. Neutralizing Antibody Study Group. Neutralizing antibodies (Nab’s) to beta interferons in patients with multiple sclerosis. Presented at the American Academy of Neurology 52nd Annual Meeting, San Diego, CA, 2000. (Abstract published in Neurology, 54, Suppl. 3, 2000, p. A234.)
29. Vollmer TL. Ni W. Hadjimichael O. Multiple sclerosis treatment patterns at the end of the 20th century. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Halifax, Canada, June 2000. (Abstract published online [www.mscare.org] in the International Journal of MS Care, 2(2), 2000.)
30. Fraser C, Hadjimichael O, Vollmer T. Predictors of adherence to Copaxone therapy in individuals with relapsing-remitting multiple sclerosis. Presented at Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting in Halifax, Canada, June 2000. (Abstract published online [www.mscare.org] in the International Journal of MS Care, 2(2), 2000.)
31. Vollmer TL. Hadjimichael O. Ni W. Effect of race in the treatment of multiple sclerosis. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Halifax, Canada, June 2000. (Abstract published online [www.mscare.org] in the International Journal of MS Care, 2(2), 2000.)
32. Fraser C, Hadjimichael O, Vollmer T. Predictors of adherence to Copaxone therapy in individuals with relapsing-remitting multiple sclerosis. J Neurosci Nurs 2001;33:231-239.
33. Vollmer TL. Ni W. Hadjimichael O. Subtypes of multiple sclerosis: Biological factors and progression of disease. Presented at the 53rd Annual Meeting of the American Academy of Neurology, Philadelphia, PA, May 2001. (Abstract published in Neurology, 56, Suppl. 3, 2001, pp. A194-195.)
34. Ni W. Hadjimichael O. Vollmer TL. Rizzo M. Pain syndromes in multiple sclerosis: Severity, impact on quality of life, and treatment patterns. Presented at the 53rd Annual Meeting of the American Academy of Neurology, Philadelphia, PA, May 2001. (Abstract published in Neurology, 56, Suppl. 3, 2001, p. A98.)
35. Vollmer TL. Ni W. Hadjimichael O. Rizzo M. Biological factors and subtypes of multiple sclerosis. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Fort Worth, TX, May 2001. (Abstract published in the International Journal of MS Care, 3, 2001, p. 51.)
36. Vollmer TL. Ni W. Hadjimichael O. Rizzo M. Disability and handicap in multiple sclerosis and their effect on employment. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Fort Worth, TX, May 2001. (Abstract published in the International Journal of MS Care, 3, 2001, p. 51.)
37. Ni W. Hadjimichael O. Rizzo M. Vollmer TL. The impact of childbirth on the progression of disability in multiple sclerosis. Presented at the Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting, Forth Worth, TX, May 2001. (Abstract published in the International Journal of MS Care, 3, 2001, p. 39.)
38. Preiningerova J, Ding Z, Cannistraci C, Sun H, Vollmer T, Anderson A. Computer Assisted Volumetric Analysis of Gadolinium Enhancement in Mulitple Sclerosis(P245). Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
39. Goodman A, Blight A, Cohen J, Cross A, Katz M, Rizzo M, Vollmer T. Placebo-Controlled Double-Blinded Dose Ranging Study of Fampridine-SR in Multiple Sclerosis(P308). Presented at the Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
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40. Markovic-Plese S, Powell A, Cortez A, Vollmer T. Therapeutic Potential of Statins in Relapsing- Remitting Multiple Sclerosis(P340). Presented at the Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002
41. Goodman AD, Blight A, Cohen J, Cross A, Katz M, Rizzo MA, Vollmer TL. Placebo-controlled Double-Blinded Dose Ranging Study of Fampridine-SR in Multiple Sclerosis. ECTRIMS 2002
42. Goodman AD, Blight A, Cohen J, Cross A, Katz M, Rizzo MA, Vollmer TL. Placebo-controlled Double-Blinded Dose Ranging Study of Fampridine-SR in Multiple Sclerosis. AAN 2002
43. Rizzo M, Hadjimichael O, Buenconsejo J, Preiningerova J, Vollmer T. Spasticity in MS Patients in the NARCOMS Registry: Prevalence, Severity and Treatment Patterns Using Oral Agents And/Or Intrathecal Baclofen(P191). Presented at the Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
44. Vollmer TL, Hadjimichael O, Buenconsejo J. Quality of Life and Cost of Illness in Mitoxantrone Treated Multiple Sclerosis Patients(P185). Presented at the Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
45. Vollmer TL, Preiningerova J, Markovic-Plese S, Rizzo M, Cugger G. A Phase IIB Study of Oral Interferon Beta-1A At Two Doses in Relapsing Remitting Multiple Sclerosis Using MRI, Clinical and Immunologic Measures(P163). Presented at the Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
46. Marrie R, Cohen J, Hadjimichael O, Vollmer T. Use of Alternative Providers in Multiple Sclerosis(P63). Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Baltimore, MD, September 2002.
47. Goodman A, Cohen J, Vollmer T, Cohen R, Katz M, Blight A, Fampridine-SR Study Group. Safety and Efficacy of Fampridine-SR inMultiple Sclerosis Patients: a Phase 2 Trial. Presented at the Consortium of Multiple Sclerosis Centers (CMSC), Toronto, Canada, June 2004.
48. Kasper L, Everitt D, Leist T, Ryan K, Mascelli M, Cusmano C, Johnson K, Hartnett H, Bauman T, Fadul C, Chanon-Smith J, Markovic S, Vollmer, T. Therapeutic Intervention of Multiple Sclerosis with an IL-12/23p40 Antagonist: A Phase I Clinical Trail. Presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Vienna, Austria, October 2004.
49. Vollmer T, Wymer J, Smith R, Pope L. A Randomized Trial of AVP-923 for Treatment of Pain in Multiple Sclerosis. Presented at the Consortium of Multiple Sclerosis Centers, Orlando, FL. June 2005.
50. Liu R, Van Kaer L, LaCava A, Price M, Campagnolo D, Collins M, Young D, Vollmer T, Shi F. Autoreactive T cells mediate NK cell degeneration in autoimmune disease.
51. Bar-Or A, Jalili F, Niino M, Bodner C, Antel J, Shi F, Price M, Rhodes S, Vollmer T, Gianettoni J, Valone F, Steinman L, Garren H. Antigen-specific Immune Changes with MBP Encoding DNA Plasmid (BHT-3009) alone or Combined with Atorvastatin Multiple Sclerosis Patients. Submitted
52. Bar-Or A, Jalili F, Niino M, Bodner C, Antel J, Shi F, Price M, Rhodes S, Vollmer T, Gianettoni J, Valone F, Steinman L, Garren H. Antigen-specific immunomodulation in multiple sclerosis patients treated with MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin. Submitted
53. Liu R, LaCava A, Pollard M, Price M, Rhdoes S, Vollmr T, Sarvetnick N, Shi F. Impaired Neuroantigen Priming Determines Resistance to the Induction of Autoimunity in MyD88-Deficient Mice. Accepted AAN 2005 Meeting, Miami Beach, FL
54. Liu R, Pollard M, LaCava A, Price M, Rhodes S, Campagnolo D, Vollmer T, VanKear L, Shi F. Treatment of a B-Cell Mediated Autoimmune Disease, Myasthenia Gravis in Mice by Activation of Natural Killer T (NKT) Cells. Accepted AAN 2005 Meeting, Miami Beach, FL
55. Vollmer T, Lapierre Y, Weiner L, Oger J, Bar-Or A, Arnold D, Barkas W, Antel J, Kachuck N, Garren H, Gianettoni J, Steinman L, Valone F; Clinical trial of a MBP encoding DNA plasmid (BHT- 3009) alone or combined with atorvastatin for treatment of multiple sclerosis. Accepted ECTRIMS/ACTRIMS 2005 meeting, Thessaloniki, Greece.
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56. Vollmer T, Panitch H, Dunn S, Lublin F, O'Connor P, Bar-Or A, Freedman M, Hendin B, Gazda S, Campagnolo D, Shi F. Induction treatment with mitoxantrone (Novantrone®) preceding treatment with glatiramer acetate (Copaxone®), a multi-centre, randomised, two-arm, open-label study in RRMS patients. Accepted ECTRIMS/ACTRIMS 2005 meeting, Thessaloniki, Greece.
57. Bar-Or A, Jalili F, Niino M, Bodner C, Antel J, Shi F, Price M, Rhodes S, Vollmer T, Gianettoni J, Valone F, Steinman L, Garren H. Antigen-specific Immune Changes with MBP Encoding DNA Plasmid (BHT-3009) alone or Combined with Atorvastatin Multiple Sclerosis Patients. Submitted.
58. Garren H, Antel J, Bar-Or A, Bodner C, Campagnolo D, Gianettoni J, Jahili F, Kachuck N, Lapierre Y, Nino M, Oger J, Price M, Rhodes S, Shi F, Valone F, Vollmer T, Weiner L, Steinman L. Phase I/II trial of a MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin for treatment of multiple sclerosis. European Neurological Society 2006 Annual Meeting; Lausanne, Switzerland.
59. Garren H, Antel J, Bar-Or A, Bdner C, Campagnolo D, Gianettoni J, Jalili F, Kachuck N, Lapierre Y, Niino M, Oger J, Price M, Rhodes S, Robinson W, Shi F, Valone F, Vollmer T, Steinman L. Phase I/II trial of a MBP encoding DNA plasmid (BHT-3009) alone or combined with atorvastatin for treatment of MS. International Society of Neuroimmunology 2006 Annual Meeting; Nagoya, Japan.
60. Hadjimichael, O., Kerns, R., Rizzo M., Vollmer T. (2007). Persistent pain and uncomfortable sensations in persons with multiple sclerosis. Pain, 127, 1-2, 35-41
61. Bar-Or A, Gibbs E, Niino M, Aziz T, Alatab S, Shi F, Campagnolo D, Jalili F, Rhodes S, Yamashita T, Fan B, Freedman M, Panitch H, Arnold D, Vollmer T, Oger J. Tracking in vivo immune modulation in MS patients treated with Glatiramer Acetate (GA) alone, or with GA preceded by Mitoxantrone, provides novel insights into the mode of action of therapeutic strategies that combine immune suppression and immune deviation. Neurology 2007 March 20:68(12);S1.
62. Hauser S, Waubant E, Arnold D, Vollmer T, Antel J, Fox R, Bar-Or A, Sarkar N, Langer-Gould A, Panzara M, Smith C. A phase II randomized, placebo-controlled multicenter trial of rituximab in adults with relapsing remitting multiple sclerosis (RRMS). Neurology 2007 March 20:68(12);S1.
63. Cutter G, Yadavalli R, Marrie R, Tyry T, Campagnolo D, Bullock B, Vollmer T. Changes in the sex ratio over time in multiple sclerosis. Neurology 2007 March 20:68(12);S1.
64. Bullock B, Tyry T, Cutter G, Marrie R, Vollmer T, Campagnolo D. Birthplace variation among US residents with MS. Neurology 2007 March 20:68(12);S1.
65. Marrie R, Cutter G, Tyry T, Vollmer T, Campagnolo D. Patients with multiple sclerosis smoke more than the general population. Neurology 2007 March 20:68(12);S1.
66. Bullock B, Tyry T, Cutter G, Marrie R, Vollmer T, Campagnolo D. Seasonal patterns of birth in NARCOMS MS registry. Neurology 2007 March 20:68(12);S1.
67. Vollmer T, Campagnolo D, Panitch H, Bar-Or A, Arnold D. Reductions in MRI disease activity and relapse rates in observed after induction of shortterm immunosuppression with mitoxantrone followed by longterm glatiramer acetate (GA) are maintained at 24 months in patients with relapsing remitting multiple sclerosis (RRMS). Neurology 2007 March 20:68(12);S1.
68. Arnold D, Bar-Or A, Freedman M, Gazda S, Panitch H, Vollmer T. Reductions in Gd enhancing lesions observed with glatiramer acetate following a brief and low dose course of mitoxantrone in patients with relapsing remitting multiple sclerosis (RRMS) are paralleled by favorable effects on MRI markers of disease burden and black hole evolution. Neurology 2007 March 20:68(12);S1.
69. Foley F, Zemon V, Campagnolo D, Marrie RA, Cutter G, Tyry T, Devitt M, Miller T, Sipski M, and Vollmer T. (2007). Validation of the MS Intimacy and Sexuality Questionnaire in large national sample. Poster S33 Presented at the 21st Annual CMSC Meeting in Washington, DC, June, 2007. (Abstract published in International Journal of MS Care, 9,2, 58-59.)
70. Foley F, Zemon V, Campagnolo D, Devitt M, Tyry T, Marrie RA, Cutter G, Sipski M, & Vollmer T. (2007). The Epidemiology of sexual dysfucntion in multiple sclerosis in the United States. Platform presentation P15 at the 21st Annual CMSC Meeting in Washington, DC, June 2007. (Abstract published in International Journal of MS Care, 9,2, 47-48.)
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71. Hadjimichael, O, Vollmer, T, Oleen-Burkey, M (2008). Fatigue characteristes in multiple sclerosis: the North American Research Committee on Multiple Sclerosis (NARCOMS) survey. Health and Quality of Life Outcomes, 6, 100.
72. Moberly J, Zahir H, Ford D, Truitt, KE, Carothers, TJ, Chen, S, Shi M, Vollmer T An adaptive multiple Ascending dose study using lymphocytes as a primary biomarker for early clinical evaluation of a S1P receptor Modulator for treatment of multiple sclerosis ACTRIMS 2009
73. Eckert B, Smith KW, Trisolini M, Vollmer T Prescription Medication use among MS adults on disease Modifying therapies. CMSC Abstract #2 January 22, 2009.
74. Eckert B, Smith KW, Trisolini M, Vollmer T Burden of Disease-Modifying therapy injections administration for MS caregivers. CMSC Abstract #1 January 22, 2009.
75. Tyry, T., Vollmer, T., Davis, P., Marrie, R.A., Cutter, G., & Campagnolo, D. (2008) Natural history of MS Among patients treated with SC interferon B-1b. Poster S87 presented at the CMSC conference in Denver, May 2008. (Abstract published in International journal of MS Care, 10, S1, 38.) MS caregivers. CMSC Abstract #1 January 22, 2009.
76. Salter AS, Tyry T, Moreau R, Marrie RA, Vollmer T, Cutter, GR. (2010) Estimating the Probability of Employment Status Transitions and Exploration of Influential Factors. Poster presentation 2010 AAN Annual Meeting Toronto.
77. Moreau R, Salter A, Tyry T, Marrie RA, Vollmer T, Cutter GR. (2010) Hand Function, Mobility and Employment Status in the NARCOMS Registry. Abstract presented at the 2010 AAN annual meeting Toronto.
78. Volmer T, Bar-Or A, Campagnolo D, Panitch H, and Arnold D. (2010) Short-term Immunosuppression with Mitoxantrone Followed by Long-Term Glatiramer Acetate vs Glatiramer Acetate Alone: Results at 60 Months in Patients with Relapsing Multiple Sclerosis. Abstract,2010 American Academy of Neurology annual meeting, Toronto, Canada
79. Zahir H, Moberly JB, Ford D, Truitt KE, Bar-Or A, Vollmer T. (2010) Differential effects of a selective sphingosine1-phosphate receptor 1 (S1P1) Modulator (CS-0777) on circulating lymphocyte subsets in multiple sclerosis patients. Poster presentation 2010 AAN annual meeting.
80. Calabresi PA, Goodin D, Jeffrey D, Lublin FD, Rammohan K, Reder AT, Vollmer T, Stites T, Li B, Gottschalk R and Malhotra M on behalf of the FREEDOMS II Study Group. (2010) Oral fingolimod (FTY720) in relapsing-remitting multiple sclerosis: baselilne patient demographics and disease characteristics from a 2-year phase III trial (FREEDOMS II). Abstract/Poster presentation given at 2010 AAN annual meeting, Toronto; also presented at the Annual CMSC Meeting, June, 2010, San Antonio, TX
81. Ramesh CN, Vollmer T, Bomprezzi R, Campagnolo D, Jacolik R. A relative deficiency in CD16+/Perforin + Lymphocytes (NK cells) in multiple sclerosis is corrected by glatiramer acetate (GA) treatment. Abstract given at ACTRIMS meeting San Antonio, TX June, 2010
82. Ramesh CN, Vollmer TL, Bomprezzi R, Campagnolo D and Jocolik R. Plasma visfatin elevation in multiple Sclerosis. Abstract given at ACTRIMS meeting, San Antonio, TX June, 2010
83. Marrie, RA, Cutter G, Vollmer T, and Tyry T. Physical Comorbidities Are Associated with an Increased Risk of Depression in Multiple Sclerosis. Abstract accepted, American Academy of Neurology Annual Meeting Toronto, Canada 2010.
84. Marrie RA, Cutter G, Vollmer T, and Tyry T. Comorbidity is Associated with Greater Decrements in Quality of Life over Two Years in MS. Abstract #264AAN10D1 American Academy of Neurology Annual Meeting Toronto, Canada 2010
85. Campagnolo, D, Bomprezzi R, Vollmer T. Recirculating phagocytes are a novel source of biomarkers for multiple sclerosis. Abstract C-99 accepted for presentation to the American Academy of Clinical Chemistry annual meeting in Anaheim, CA July, 2010
86. Schmidt H, Loud S, Venkatesan A, Goins J, Frohman E, Taylor S, Sadiq S, Puccio L, Thrower B, Iski E, Riskind P, Weaver J, Bomprezzi R, Bullock B, Kinkel RP, Konkel S, Racke M, McGowan J, Vollmer T, Edward S, Steinman L, Lebus D, Greenberg B. The Accelerated Cure Project Biorepository—enabling the discovery of biomarkers in MS and other demyelinating diseases. Poster
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P963 presented at The Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 15th Annual conference of Rehabilitation in MS October 12—16, 2010, Gothenburg, Sweden.
87. Salter AR, Cofield SS, Vollmer T, Cutter GR. Timing of birth in United States-born multiple sclerosis population. Poster P617 presented at The Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 15th Annual conference of Rehabilitation in MS October 12—16, 2010, Gothenburg, Sweden.
88. “Return to ECTRIMS: Updates from ECTRIMS for Treatment and Research in MS” to area Neurologists, Denver, Colorado February 23, 2011.
89. Vollmer, TL, Tyry, T, Salter A, Cutter G, Marrie R. Is trigeminal neuralgia more prevalent in certain groups of multiple sclerosis patients? Poster presentation to the AAN Annual meeting, Honolulu, HI April, 2011.
90. Fox R, Salter A, Alster JM, Cutter G, Dawson NV, Johnson S, Miller D, Tyry T, Vollmer T, Wells B, Kattan M. Do multiple sclerosis patients understand Risk? Survey results from the NARCOMS Registry. Poster presentation at the AAN annual meeting, Honolulu, Hawaii, April, 2011
91. Moreau RL, Salter AR, Marrie R, Tyry T, Cutter G, Vollmer T. Comorbidities, smoking habits, and their connection with secondhand smoke. Poster presentation to the AAN annual meeting, Honolulu, Hawaii, April, 2011
92. Miller D, Alster JM, Cutter G, Dawson NV, Johnson S, Kattan M, Salter A, Tyry T, Wells B, Vollmer T, Fox R. Patient preferences for information seeking and decision resources: survey results from the NARCOMS registry. Poster presentation to the AAN annual meeting, Honolulu, Hawaii, April, 2011
93. Fox R, Salter A, Alster JM Dawson NV, Johnson S, Kattan M, Miller D, Tyry T, Wells B, Vollmer T, Cutter G. Risk tolerance in MS patients: survey results from the NARCOMS registry. Poster presentation to the AAN annual meeting Honolulu, Hawaii, April, 2011
94. Vollmer TL, Robinson MR, Risser RC, Malcolm SK, Carlson JL. A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of central neuropathic pain associated with multiple sclerosis. Poster presented at the annual ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis) annual meeting. Amsterdam, The Netherlands, October 21, 2011.
95. Vollmer TL, Sorensen PS, Arnold DL on behalf of the BRAVO Study Group. A Placebo-Controlled and Active Comparator Phase III Trial (BRAVO) for Relapsing-Remitting Multiple Sclerosis. Poster presented at the Annual ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis)annual meeting, Amsterdam, The Netherlands on October 22, 2011.
96. Nayak R, Vollmer T, Bomprezzi R, Jacolik R. A circulating biomarker for the therapeutic response in multiple sclerosis. Poster presentation ECTRIMS (European Committee for Treatment and Research in Multiple Sclerosis) annual meeting in Amsterdam, The Netherlands
October 21, 2011
97. Volmer T, Comi G, Sorensen PS, Arnold D, Filippi M, Statinova O, Kobys t, Becker E, Jeffrey D, Montalban X, Kappos L, Boyko A, Selmaj K, Zipp F, Havrdova E, Cohen J. Clinical efficacy of laquinimod for the treatment of multiple Sclerosis; pooled analyses from the ALLEGRO and BRAVO Phase III trials. Poster and abstract presented at the 64th Annual American Academy of Neurology meeting, New Orleans, LA April 24, 2012
98. Comi G, Vollmer T, Sorensen PS, Arnold D, Filippi M, Statinov O, Kobys T, Becker E, Jeffrey D, Montalban X, Kappos L, Boyko A, Selmaj K, Zipp F, Havrdova E, Cohen J. Pooled analyses from the ALLEGRO and BRAVO trials on the safety and tolerability of laquinimod as a multiple sclerosis treatment. Abstract and poster presented at the 64th Annual American Academy of Neurology Meeting, New Orleas, LA April 25, 2012.
99. Campbell J, McQueen RB, Corboy J, Vollmer T, Nair K. New versus old: long-term comparative effectiveness research projections for disease modifying therapies in relapsing-remitting multiple sclerosis. Abstract and poster presented at 64th Annual American Academy of Neurology meeting, New Orleans, LA April 26, 2012.
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100. Vollmer T, Due B. A double-blind, placebo-controlled, phase2, 26-week DreaMS trial of a selective S1P receptor agnonists ONO 4641 in patients with relapsing-remitting multiple sclerosis. Abstract and poster presentation at the 64th Annual American Academy of Neurology meeting, New Orleans, LA, April 25, 2012
13.4
Bibliography—Non peer reviewed publications
1. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 1999. 18(2):2
2. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 1999. 18(3):2.
3. Vollmer TL. Mitoxantrone: A New Treatment for Multiple Sclerosis. Multiple Sclerosis Quarterly
Report. 1999. 18(4):1, 3-5
4. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 1999. 18(4):2
5. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2000. 19(1):2.
6. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2000. 19(4):2.
7. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2000. 19(3):2.
8. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2000. 19(2):2.
9. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2001. 20(4):2.
10. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2001. 20(2):2.
11. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2001. 20(1):2.
12. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2001. 20(3):2.
13. Vollmer TL. The Changing Definition of Multiple Sclerosis. Multiple Sclerosis Quarterly Report.
2001. 20(3):24-25.
14. Vollmer TL. Ethical Considerations of Clinical Trials in Multiple Sclerosis Treatment. Multiple

Sclerosis Quarterly Report. 2001. 20(3):21-23.
15. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2002. 21(1):2.
16. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2002. 21(2):2
17. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2002. 21(3):2
18. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2002. 21(4):2.
19. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2003. 22(1):2
20. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2003. 22(2):2.
21. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2003. 22(3):2
22. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2003. 22(4):2
23. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2004. 23(1
24. Vollmer TL. Letter from the Editor. Multiple Sclerosis Quarterly Report. 2004. 23(2):2
14. Patents Held
Nicotinic Attenuation of CNS Inflammation and Autoimmunity U.S. Application No. 13/063,713, which is the national phase of International PCT Patent Application No. PCT/US09/56671, an application claiming the benefit of U.S. Prov. App. No. 61/096,170
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Labels: Avonex, Betaseron, Copaxone, Novantrone, Rebif, Rituxan, Tysabri